79593-50-3Relevant academic research and scientific papers
The total synthesis of (-) -strempeliopine: Via palladium-catalyzed decarboxylative asymmetric allylic alkylation
An, Yi,Chen, Fener,Li, Weijian,Li, Yaling,Tang, Pei,Wang, Zhenzhen,Wu, Mengjuan,Xue, Yansong
supporting information, p. 1402 - 1405 (2022/02/09)
In the work reported herein, the concise and enantioselective total synthesis of the Schizozygine alkaloid (-)-strempeliopine was developed. This synthetic strategy featured the palladium-catalyzed decarboxylative asymmetric allylic alkylation of N-benzoy
Room-temperature Pd-catalyzed methoxycarbonylation of terminal alkynes with high branched selectivity enabled by bisphosphine-picolinamide ligand
Chen, Fen-Er,Ke, Miaolin,Liu, Ding,Ning, Yingtang,Ru, Tong
supporting information, p. 1041 - 1044 (2022/01/28)
We report the room-temperature Pd-catalyzed methoxy-carbonylation with high branched selectivity using a new class of bisphosphine-picolinamide ligands. Systematic optimization of ligand structures and reaction conditions revealed the significance of both
Pd-Catalyzed Carbonylation of Vinyl Triflates to Afford α,β-Unsaturated Aldehydes, Esters, and Amides under Mild Conditions
Zhang, Shaoke,Neumann, Helfried,Beller, Matthias
, p. 3528 - 3532 (2019/05/24)
An efficient and general protocol for the synthesis of α,β-unsaturated aldehydes, esters, and amides via carbonylation of vinyl triflates including derivatives of camphor, ketoisophorone, verbenone, and pulegone was developed. Crucial for these transformations is the use of a specific palladium catalyst containing a pyridyl-substituted dtbpx-type ligand. This procedure also allows for an easy access of dicarbonylated products from the corresponding ketones.
2-pyrimidylphosphines: A new class of ligands for transition metal catalysis
Reetz, Manfred T.,Demuth, Ralf,Goddard, Richard
, p. 7089 - 7092 (2007/10/03)
The synthesis of 2-pyrimidyldiphenylphosphine (2), bis-2- pyrimidylphenyl-phosphine (3) and tris-2-pyrimidylphosphine (4) is described. Ligand 2 forms cationic complexes with palladium(II) in which four-membered P/N-chelates are involved, leading to a ver
Efficient Synthesis of Methyl 2-(tert-Butyl)acrylate and Analogous Esters
Xu, Long-He,Kuendig, Ernst Peter
, p. 1480 - 1484 (2007/10/02)
The title products are prepared via an efficient three-step synthesis which involves hydroalumination of methyl propiolate and Lewis-acid-promoted reaction with acetone in the presence of BF3 followed by two highly selective SN2' reactions.The
