79695-54-8Relevant academic research and scientific papers
SYNTHETIC UTILITY OF A FLUORINE-FACILITATED CLAISEN REARRANGEMENT: A NOVEL SYNTHETIC METHOD FOR 2,4-ALKANEDIENOIC ACIDS USING 2,2,2-TRIFLUOROETHYL PHENYL SULFOXIDE
Nakai, Takeshi,Tanaka, Kiyoshi,Ogasawara, Kyo,Ishikawa, Nobuo
, p. 1289 - 1292 (2007/10/02)
A novel synthetic method for 2,4-alkadienoic acids from allylic alcohols and 2,2,2-trifluoroethyl phenyl sulfoxide is described which involves the in situ Claisen rearrangement facilitated by the fluorine.This method was applied to the stereocontrolled synthesis of pellitorine, a natural insecticide.
