796964-13-1

Basic information

• Product Name: 1-METHYL-2-PHENYL-3-PROPYLINDOLE
• Synonyms: 1-METHYL-2-PHENYL-3-PROPYLINDOLE
• CAS NO: 796964-13-1
• Molecular Formula: C18H19N
• Molecular Weight: 249.35
• Mol File: 796964-13-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-METHYL-2-PHENYL-3-PROPYLINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-2-PHENYL-3-PROPYLINDOLE(796964-13-1)
• EPA Substance Registry System: 1-METHYL-2-PHENYL-3-PROPYLINDOLE(796964-13-1)

Safety Data

• Hazardous Substances Data: 796964-13-1(Hazardous Substances Data)

Usage

General Description

1-Methyl-2-phenyl-3-propylindole, also known as 3-Methyl-2-phenylindole, is a chemical compound with the molecular formula C17H17N. It is a derivative of the indole class of compounds, which are commonly found in various natural products and pharmaceuticals. This particular chemical is known for its potential use in medicinal and research applications, particularly in the development of drugs targeting the central nervous system. Its structure and properties make it a promising candidate for studying the interaction of indole derivatives with biological receptors, as well as for the development of new therapeutic agents for various neurological disorders and conditions. Despite its potential, 1-Methyl-2-phenyl-3-propylindole is also a controlled substance due to its psychoactive properties, and it is important to use and handle it with caution in a controlled laboratory setting.

Upstream product

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• 103-67-3 benzyl-methyl-amine 
• 1486473-69-1 N-benzyl-2-(buta-1,3-dien-1-yl)-N-methylaniline 
• 446-52-6 2-Fluorobenzaldehyde 
• 85-91-6 Methyl N-methylanthranilate 
• 29055-08-1 N-methyl-o-aminobenzyl alcohol 
• 869301-69-9 (2-benzenesulfonylmethyl-phenyl)-methyl-carbamic acid tert-butyl ester 
• 240493-91-8 (2-bromomethyl-phenyl)-methyl-carbamic acid tert-butyl ester 
• 240493-90-7 tert-butyl (2-(hydroxymethyl)phenyl)(methyl)carbamate 
• 869301-70-2 [2-((Z)-1-Benzenesulfonyl-2-phenyl-vinyl)-phenyl]-methyl-amine 
• 107-08-4 1-iodo-propane 

Relevant articles and documents

Co(III)-Catalyzed, Internal and Terminal Alkyne-Compatible Synthesis of Indoles

A Co(III)-catalyzed, internal and terminal alkyne-compatible indole synthesis protocol is reported herein. The N-amino (hydrazine) group imparts distinct, diverse reactivity patterns for directed C-H functionalization/cyclization reactions. Notable synthetic features include regioselectivity for a meta-substituted arylhydrazine, regioselectivity for a chain-branched terminal alkyne, formal incorporation of an acetylenic unit through C2-desilylation on a C2-silylated indole derivative, formal inversion of regioselectivity through consecutive C3-derivatization and C2-desilylation processes, and formal bond migration for a linear-chain terminal alkyne.

A Versatile, Traceless C-H Activation-Based Approach for the Synthesis of Heterocycles

A versatile, traceless C-H activation-based approach for the synthesis of diversified heterocycles is reported. Rh(III)-catalyzed, N-amino-directed C-H alkenylation generates either olefination products or indoles (in situ annulation) in an atom- and step-economic manner at room temperature. The remarkable reactivity endowed by this directing group enables scale-up of the reaction to a 10 g scale at a very low catalyst loading (0.01 mol %/0.1 mol %). Ex situ annulation of olefination product provides entry into an array of heterocycles.

Novel synthesis of 2-aryl and 2,3-disubstituted indoles by modified double elimination protocol

(Chemical Equation Presented) Syntheses of 2-aryl and 2,3-substituted indoles were realized by modified double elimination protocol. Under basic conditions, vinyl sulfones derived from the reaction of 2-aminobenzyl sulfone with benzaldehydes underwent cyclization and alkylation followed by elimination of sulfinic acid to afford 2,3-substituted indoles.