79758-03-5Relevant academic research and scientific papers
Biarylmethoxy isonipecotanilides as potent and selective inhibitors of blood coagulation factor Xa
Lopopolo, Gianfranco,Fiorella, Filomena,De Candia, Modesto,Nicolotti, Orazio,Martel, Sophie,Carrupt, Pierre-Alain,Altomare, Cosimo
, p. 180 - 191 (2012/01/05)
New chloro-substituted biarylmethoxyphenyl piperidine-4-carboxamides were synthesized and assayed in vitro as inhibitors of the blood coagulation enzymes factor Xa (fXa) and thrombin. An investigation of effects of the amidine and isopropyl groups attache
2,6-DISUBSTITUTED PYRIDINES AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS
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Page/Page column 69, (2009/07/17)
Disclosed are compounds of formula (I) wherein R1 and R2 are independently selected from hydrogen, halo, CF3, C1-4alkyl and allyl; Y represents (II), (III), (IV) or (V) wherein R3 represents CF3 or C1-4alkyl; and R3a represents CF3 or C1-4alkyl.
