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4-CHLORO-4'-METHYL-1,1'-BIPHENYL, with the molecular formula C13H11Cl, is a chlorinated biphenyl derivative featuring a methyl substituent on one of its phenyl rings. This chemical compound is utilized in a variety of industrial and research applications, such as a starting material for synthesizing other organic compounds and as a reference standard in analytical chemistry. Due to its toxic nature and potential harm to human health and the environment, careful handling and usage are imperative.

19482-11-2

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19482-11-2 Usage

Uses

Used in Chemical Synthesis:
4-CHLORO-4'-METHYL-1,1'-BIPHENYL is used as a starting material in the synthesis of other organic compounds, contributing to the creation of a diverse range of chemical products.
Used in Analytical Chemistry:
In the field of analytical chemistry, 4-CHLORO-4'-METHYL-1,1'-BIPHENYL serves as a reference standard, aiding in the calibration and validation of analytical methods and instruments.
Used in Research Applications:
4-CHLORO-4'-METHYL-1,1'-BIPHENYL is employed in research settings to study the properties and reactions of chlorinated biphenyls and their derivatives, furthering scientific understanding in organic chemistry.
Used in Industrial Applications:
4-CHLORO-4'-METHYL-1,1'-BIPHENYL finds use in various industrial processes, where its unique structural features and reactivity are leveraged to produce specific chemical products or intermediates.
It is crucial to note that due to the toxic and potentially harmful nature of 4-CHLORO-4'-METHYL-1,1'-BIPHENYL, strict safety measures and environmental considerations must be adhered to during its use in any application.

Check Digit Verification of cas no

The CAS Registry Mumber 19482-11-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,8 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 19482-11:
(7*1)+(6*9)+(5*4)+(4*8)+(3*2)+(2*1)+(1*1)=122
122 % 10 = 2
So 19482-11-2 is a valid CAS Registry Number.

19482-11-2Relevant articles and documents

Transformation of Trifluorotoluenes Triggered by Titanium(IV) Chloride-Catalyzed Hydrodefluorination using Hydrosilanes

Yamada, Takayuki,Saito, Kodai,Akiyama, Takahiko

, p. 62 - 66 (2016)

The titanium tetrachloride-catalyzed hydrodefluorination reaction of trifluorotoluene derivatives was developed using triethylsilane as the reducing agent. The reaction produced various toluene derivatives with high chemoselectivities by means of readily accessible reagents. This hydrodefluorination process was extended to the intramolecular Friedel-Crafts benzylation reaction, furnishing polycyclic aromatics of various ring sizes in good yields.

A highly efficient heterogeneous montmorillonite K-10-supported palladium catalyst for Suzuki-Miyaura cross-coupling reaction in aqueous medium

Gogoi, Ankur,Chutia, Sankar Jyoti,Gogoi, Pradip K.,Bora, Utpal

, p. 839 - 844 (2014)

A heterogeneous montmorillonite K-10-supported palladium triphenylphosphine catalyst is reported for the Suzuki-Miyaura cross-coupling reaction at room temperature. A library of electronically diverse aryl bromides and arylboronic acids underwent the cross-coupling reaction at very good rates in aqueous solvent. The reusability of the catalyst was also examined and it was found to be effective up to three catalytic cycles.

Pillar[5]arene-based N-heterocyclic carbene ligand for Pd-catalysed Suzuki reaction

Xiao, Xue-Dong,Liu, Jia-Qi,Bai, Ya-Li,Wang, Rui-Hua,Wang, Jun-Wen

, p. 29 - 36 (2017)

A pillar[5]arene-based N-heterocyclic carbene ligand was prepared by reaction of bromoethoxy pillar[5]arene with excess 1-methylimidazole at 130?°C in the absence of solvent and used as a catalyst for the Suzuki coupling reaction. Excellent yields were obtained when the Suzuki reactions were carried out under ambient atmosphere in ethanol, employing 0.2?mol% ligand, 1?mol% PdCl2(CH3CN)2 and 1.5?mmol of K2CO3. The novel pillar[5]arene-based imidazolium salt is a promising material for the construction of highly active supramolecular catalytic systems.

Reusable Pd nanoparticles immobilized on functional ionic liquid co-polymerized with styrene for Suzuki reactions in water-ethanol solution

Wang, Jiayi,Song, Gonghua,Peng, Yanqing

, p. 1477 - 1480 (2011)

Co-polymer of 3-(2,3-dihydroxypropyl)-1-vinylimidazolium chloride and styrene was synthesized and used as a support of Pd nanoparticles. The Pd@poly-Sty-co-diOH-Cl catalyst can efficiently catalyze Suzuki reactions for a wide range of aryl iodides and bromides with 0.05 mol % Pd at 70 °C in water-ethanol solution under air, and the catalyst can be recycled and reused for several times without significant loss of activity.

Engineering of highly active Au/Pd supported on hydrogenated urchin-like yolk@shell TiO2 for visible light photocatalytic Suzuki coupling

Rohani, Sahar,Ziarati, Abolfazl,Ziarani, Ghodsi Mohammadi,Badiei, Alireza,Burgi, Thomas

, p. 3820 - 3827 (2019)

Efficient smart photocatalysts and their surface engineering are necessary for the effective conversion of light energy into chemical energy in photocatalyzed organic reactions. Herein, we designed a hydrogenated urchin-like yolk@shell TiO2 structure decorated with Au and Pd nanoparticles (HUY@S-TOH@AuPd) as a robust photocatalyst for C-C coupling reactions. The resulting architecture exhibits considerable photocatalytic performance in Suzuki coupling reactions under visible light irradiation with a turnover frequency (TOF) value as high as 7095 h-1. The beauty of this engineered structure lies on the following four points: (I) the urchin-like structure provided a large accessible surface area for high light harvesting as well as high noble metal anchoring; (II) the yolk@shell mesoporous architecture improved the absorption of light by multiple scattering; (III) the presence of Ti3+ species on the surface of TiO2 decreased the band gap of the structure to the visible region; (IV) the enriched electron density of Pd through the injection of hot electrons from Au as well as the flow of electrons from the titanium dioxide semiconductor to the metals accelerated the rate-determining step. The merging of bimetallic plasmonic nanoparticles and urchin like yolk-shell hydrogenated titanium dioxide architecture can open an avenue for designing photocatalysts with high stability and promising activity as well as high direct harvesting of visible light for a broad range of photocatalytic organic reactions.

Desulfinylative Pd-catalyzed coupling reaction of arenediazonium salt with aryl sulfinates to give unsymmetrical biaryls

Gund, Sitaram Haribhau,Balsane, Kishor Eknath,Nagarkar, Jayashree Milind

, p. 2936 - 2939 (2017)

An efficient route for the synthesis of unsymmetrical biaryls was developed via palladium catalyzed reaction of arenediazonium salts and aryl sulfinates under inert atmosphere. This synthesis involves cascade processes. Tetrabutylammonium iodide was used as an iodide source for in situ formation of aryl iodide, followed by desulfinylative cross-coupling reaction between aryl sulfinates and aryl iodides. A wide range of biaryls were selectively prepared in one pot from simple substrates in good to excellent yields.

Mesoporous palladium-copper ferrites as highly efficient and magnetically separable catalysts for Suzuki coupling reaction

Tong, Jinhui,Su, Lingdi,Bo, Lili,Cai, Xiaodong,Zhang, Qianping,Wang, Qizhao

, p. 240 - 246 (2016)

Mesoporous Cu-Pd ferrites were prepared by using MCM-41 and SBA-15 mesoporous molecular sieves as hard templates and well characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), ICP-atomic emission spectroscopy, N2 adsorption-desorption and X-ray photoelectric spectroscopy (XPS). Compared with samples prepared by the sol-gel auto-combustion methods, the as-prepared mesoporous ferrites have shown uniform pore size and much higher specific surface areas. The samples showed a remarkably high activity in connection with the Suzuki coupling reaction, especially Cu0.99Pd0.01Fe2O4 prepared by using MCM-41 as template obtained an excellent TOF as high as 36.9 × 103 h-1 and no obvious decrease in the activity was observed after ten consecutive runs.

Pd nanoparticles immobilized on the magnetic silica–chitosan nanocomposite (NiFe2O4@SiO2@CS-Pd NPs) promoted the biaryl synthesis

Rafiee, Fatemeh,Hosseini, S. Azam

, p. 1993 - 2001 (2019)

NiFe2O4 nanoparticles have been prepared by co-precipitation procedure and coated with SiO2 following the St?ber process. Then, chitosan was covalently connected with silica to provide an excellent stabilizer and biosupport for the immobilization of Pd nanoparticles. This magnetic bionanocatalyst was characterized by Fourier transform infrared spectroscopy, field-emission scanning electron microscope, transmission electron microscope, energy-dispersive X-ray, X-ray powder detection, vibrating sample magnetometer, inductively coupled plasma atomic emission spectroscopy techniques and CHN analysis. The NiFe2O4@SiO2@CS-Pd NPs exhibited high activity for the Suzuki coupling reactions of various aryl halides with arylboronic acids. Moreover, this catalyst could be recovered magnetically and recycled for nine times without significant loss of its activity.

Palladium(II) thiosemicarbazone-catalyzed Suzuki-Miyaura cross-coupling reactions of aryl halides

Pandiarajan, Devaraj,Ramesh, Rengan,Liu, Yu,Suresh, Rajamanickam

, p. 33 - 37 (2013)

A new air-and moisture-stable palladium(II) complex bearing pyridoxal thiosemicarbazone ligand has been synthesized. The synthesized complex was characterized by analytical and spectral methods. The molecular structure of the complex was confirmed by X-ray diffraction method. The palladium(II) complex was used as potential catalyst for Suzuki-Miyaura coupling reaction of several aryl halides under optimized conditions.

Structuring Pd Nanoparticles on 2H-WS2 Nanosheets Induces Excellent Photocatalytic Activity for Cross-Coupling Reactions under Visible Light

Raza, Faizan,Yim, Dabin,Park, Jung Hyun,Kim, Hye-In,Jeon, Su-Ji,Kim, Jong-Ho

, p. 14767 - 14774 (2017)

Effective photocatalysts and their surface engineering are essential for the efficient conversion of solar energy into chemical energy in photocatalyzed organic transformations. Herein, we report an effective approach for structuring Pd nanoparticles (NPs) on exfoliated 2H-WS2 nanosheets (WS2/PdNPs), resulting in hybrids with extraordinary photocatalytic activity in Suzuki reactions under visible light. Pd NPs of different sizes and densities, which can modulate the photocatalytic activity of the as-prepared WS2/PdNPs, were effectively structured on the basal plane of 2H-WS2 nanosheets via a sonic wave-assisted nucleation method without any reductants at room temperature. As the size of Pd NPs on WS2/PdNPs increased, their photocatalytic activity in Suzuki reactions at room temperature increased substantially. In addition, it was found that protic organic solvents play a crucial role in activating WS2/PdNPs catalysts in photocatalyzed Suzuki reactions, although these solvents are generally considered much less effective than polar aprotic ones in the conventional Suzuki reactions promoted by heterogeneous Pd catalysts. A mechanistic investigation suggested that photogenerated holes are transferred to protic organic solvents, whereas photogenerated electrons are transferred to Pd NPs. This transfer makes the Pd NPs electron-rich and accelerates the rate-determining step, i.e., the oxidative addition of aryl halides under visible light. WS2/PdNPs showed the highest turnover frequency (1244 h-1) for photocatalyzed Suzuki reactions among previously reported photocatalysts.

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