79759-69-6

Upstream product

• 79759-06-1 4-Chloro-N₂-(4-methoxyphenyl)benzene-1,2-diamine 
• 124-38-9 carbon dioxide 
• 1613081-71-2 C₁₃H₁₁ClN₂O₂ 
• 100-00-5 4-chlorobenzonitrile 
• 104-94-9 4-methoxy-aniline 
• 92022-96-3 N-(5-chloro-2-nitrophenyl)-N-(4-methoxyphenyl)amine 
• 79759-20-9 [4-Chloro-2-(4-methoxy-phenylamino)-phenyl]-carbamic acid ethyl ester 

Downstream Products

• 79759-70-9 5-Chloro-3-(4-methoxy-phenyl)-1-methyl-1,3-dihydro-benzoimidazol-2-one 

Relevant academic research and scientific papers

Aryliminophosphoranes as Key Intermediates in the One-Pot Synthesis of 1-Aryl-1,3-dihydro-2H-benzimidazol-2-ones from N-Aryl-2-nitrosoanilines and Carbon Dioxide under Mild Metal-Free Conditions

A new and convenient protocol is presented for the synthesis of 1-arylbenzimidazol-2-ones by a one-pot reaction of N-aryl-2-nitrosoanilines using solid carbon dioxide as a source of the key carbonyl moiety. The metal-free process is carried out under mild conditions and is compatible with a variety of substituents. The atom economy of the synthesis of the starting nitrosoanilines, accomplished by substitution of hydrogen, makes the entire synthesis of the target compounds environmentally friendly.

RECEPTOR FUNCTION REGULATING AGENT

The present invention relates to a GPR40 receptor function regulator comprising a fused imidazole compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof. The GPR40 receptor funct