798574-25-1Relevant academic research and scientific papers
Efficient and Easy Access to Optically Pure Tetrasubstituted Tetrahydrofurans via Stereoselective Opening of C2-Symmetric Epoxide and Aziridine Rings
Kumar Kondapi, Venkata Pavan,Soueidan, Olivier-Mohamad,Hosseini, Seyedeh Nargess,Jabari, Nauras,West, Frederick G.
, p. 1367 - 1379 (2016)
An efficient and facile protocol to functionalize position C-3 of 2,5-anhydro-D-mannitol via diastereoselective ring opening of a C2-symmetric epoxide 2,5:3,4-dianhydro-D-allitol 3 has been developed. This method is protecting-group-free, high-
Ring-expanded analogues of natural oxetanocin
Nair, Vasu,Chun, Byoung-Kwon,Vadakkan, Jean John
, p. 10261 - 10268 (2007/10/03)
Synthesis of ring-expanded analogs of the natural compound, oxetanocin is described. The starting material for the synthesis of the series, 4-7, was d-glucosamine and introduction of the base moiety was done through the stereochemically appropriate epoxid
Synthesis of 3-deoxy-3-nucleobase-2,5-anhydro-D-mannitol: A novel class of hydroxymethyl-branched isonucleosides
Lei,Min,Zhang
, p. 2899 - 2906 (2007/10/03)
A concise synthesis of 3-deoxy-3-nucleobase-2,5-anhydro-D-mannitol 6(a- d) has been achieved, using the deamination of 2-amino-2-deoxy-D-glucose to construct in one step the sugar skeleton with the desired sense of chirality at each asymmetric center. The selective dibenzoylation of 2,5-anhydro-D- mannitol 9 was investigated, and the key epoxide intermediate 13 was obtained in good yield via an intramolecular Mitsunobu reaction. The process of opening of epoxide 13 by nucleobases appeared to be regioselective. (C) 2000 Elsevier Science Ltd.
