799278-98-1

Upstream product

• 611-71-2 (R)-Mandelic Acid 
• 799278-96-9 (2S,5R,1'S)-2-(tert-butyl)-5-phenyl-5-[1'-phenyl-1'-(2-methoxyethoxymethoxy)methyl]-1,3-dioxolan-4-one 
• 799279-02-0 (2S,5S,1'S)-2-(tert-butyl)-5-phenyl-5-[1'-phenyl-1'-(2-methoxyethoxymethoxy)methyl]-1,3-dioxolan-4-one 
• 799278-94-7 (2S,5R,1'S)-2-(tert-butyl)-5-phenyl-5-(1'-phenyl-1'-hydroxymethyl)-1,3-dioxolan-4-one 
• 100-52-7 benzaldehyde 
• 81036-97-7 (2S,5S)-2-tert-butyl-5-phenyl-1,3-dioxolan-4-one 
• 799278-97-0 (2R,3S)-2,3-diphenyl-2-hydroxy-3-(2-methoxyethoxymethoxy)propanoic acid 
• 799279-05-3 (2S,3S)-2,3-diphenyl-2-hydroxy-3-(2-methoxyethoxymethoxy)propanoic acid 

Downstream Products

• 5928-67-6 (S)-(+)-benzoin 

Relevant academic research and scientific papers

(S)-Mandelic acid enolate as a chiral benzoyl anion equivalent for the enantioselective synthesis of non-symmetrically substituted benzoins

A strategy for the enantioselective synthesis of non-symmetrically substituted benzoins from (S)-mandelic acid and aromatic aldehydes has been developed. This strategy is based on a diastereoselective aldol reaction of the lithium enolate of the 1,3-dioxo

Enantioselective synthesis of unsymmetrical benzoins from (S)-mandelic acid enolate and aromatic aldehydes

Highly enantioenriched unsymmetrical benzoins are obtained from (S)-mandelic acid. The reaction of the lithium enolate of the 1,3-dioxolan-4-one derived from optically active (S)-mandelic acid and pivalaldehyde with aromatic aldehydes proceeds readily to