799278-99-2Relevant academic research and scientific papers
(S)-Mandelic acid enolate as a chiral benzoyl anion equivalent for the enantioselective synthesis of non-symmetrically substituted benzoins
Blay, Gonzalo,Fernández, Isabel,Monje, Belén,Montesinos-Magraner, Marc,Pedro, José R.
experimental part, p. 881 - 890 (2011/03/19)
A strategy for the enantioselective synthesis of non-symmetrically substituted benzoins from (S)-mandelic acid and aromatic aldehydes has been developed. This strategy is based on a diastereoselective aldol reaction of the lithium enolate of the 1,3-dioxo
Enantioselective synthesis of unsymmetrical benzoins from (S)-mandelic acid enolate and aromatic aldehydes
Blay, Gonzalo,Fernández, Isabel,Monje, Belén,Pedro, José R.
, p. 8039 - 8042 (2007/10/03)
Highly enantioenriched unsymmetrical benzoins are obtained from (S)-mandelic acid. The reaction of the lithium enolate of the 1,3-dioxolan-4-one derived from optically active (S)-mandelic acid and pivalaldehyde with aromatic aldehydes proceeds readily to
