8001-25-0

Basic information

• Product Name: Olive oil
• Synonyms: OLIVAE OLEUM;OLIVE OIL;OLIVE OIL, EXTRA VIRGIN;OLIVE OIL, PURE/RIVIERA;OLIVE OIL, REFINED A;OLIVE POMACE OIL;OIL OF OLIVE;sweetoil
• CAS NO: 8001-25-0
• Molecular Weight: 0
• EINECS: 232-277-0
• Product Categories: Biochemicals and Reagents;LipidsFood&Beverage Standards;Natural Derived FatsAnalytical Standards;OBiochemicals and Reagents;OilsOther Lipid Related Products;Alphabetic;FA/FAME/Lipids/Steroids;Food&Beverage Standards;Lipid Analytical Standards;Lipids;Oils
• Mol File: 8001-25-0.mol
• Article Data: 0

Chemical Properties

• Flash Point: 225 °C
• Appearance: Yellow/Viscous Liquid
• Density: 0.9135
• Vapor Density: >1 (vs air)
• Refractive Index: 1.467-1.471
• Storage Temp.: room temp
• Solubility: Slightly soluble in ethanol (95%); miscible with ether, chloroform, light petroleum (50–70°C), and carbon disulfide.
• Water Solubility: Insoluble in water
• CAS DataBase Reference: Olive oil(CAS DataBase Reference)
• NIST Chemistry Reference: Olive oil(8001-25-0)
• EPA Substance Registry System: Olive oil(8001-25-0)

Safety Data

• Hazard Codes: Xi
• Statements: 38
• Safety Statements: 24/25
• WGK Germany: nwg
• RTECS: RK4300000
• Hazardous Substances Data: 8001-25-0(Hazardous Substances Data)

Usage

Description

Olive oil is a versatile and nutritious oil extracted from the fruit of olive trees, Olea europaea. It is characterized by a unique composition of fatty acids, with 14% total saturated acids, 77% total monounsaturated acids, and 9% total polyunsaturated acids. This rich blend of fatty acids, including C16 palmitic, C18 stearic, oleic, linoleic, and linolenic acids, contributes to its numerous health benefits and diverse applications.

Uses

Used in Food Industry:
Olive oil is used as a salad and cooking oil for its rich flavor and health benefits. It is particularly favored in Mediterranean cuisine for its use in salads, with sardines, and other dishes.
Used in Cosmetics and Personal Care Industry:
Olive oil serves as an emollient, providing moisturizing and soothing properties for the skin. It is used in the manufacturing of cosmetics and personal care products, such as lotions, creams, and balms, due to its nourishing and protective qualities.
Used in Pharmaceutical Industry:
Olive oil is utilized for the treatment of leg ulcers, thanks to its anti-inflammatory and healing properties. It can help promote skin regeneration and reduce the risk of infection.
Used in Soap Making:
Olive oil is used in the production of soaps, where its gentle and moisturizing properties make it suitable for creating mild and skin-friendly soaps.
Used in Textile Industry:
Olive oil is employed as a textile lubricant, helping to reduce friction and protect fibers during the manufacturing process.
Overall, olive oil is a multifaceted ingredient with applications spanning across various industries, from food and cosmetics to pharmaceuticals and textiles. Its unique combination of fatty acids and health benefits make it a valuable and sought-after resource.

Production Methods

Virgin olive oil is produced by crushing olives (the fruit of Olea europaea), typically using an edge runner mill. The oil is then expressed from the crushed mass solely by mechanical or other physical methods under conditions that do not cause deterioration of the oil. Any further treatment that the oil undergoes is limited to washing, decantation, centrifugation, and filtration. Refined olive oil is obtained from virgin olive oil by refining methods that do not alter the initial glyceride content of the oil.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Olive oil react with acids to liberate heat. Heat is also generated by interaction with caustic solutions. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Flammable hydrogen is generated by mixing with alkali metals and hydrides. React slowly with oxygen in the air to become rancid.

Pharmaceutical Applications

Olive oil has been used in enemas, liniments, ointments, plasters, and soap. It has also been used in oral capsules and solutions, and as a vehicle for oily injections including targeted delivery systems. It has been used in topically applied lipogels of methyl nicotinate.It has also been used to soften ear wax. Olive oil has been used in combination with soybean oil to prepare lipid emulsion for use in pre-term infants. Olive oil is used widely in the food industry as a cooking oil and for preparing salad dressings. In cosmetics, olive oil is used as a solvent, and also as a skin and hair conditioner. Types of products containing olive oil include shampoos and hair conditioners, cleansing products, topical creams and lotions, and sun-tan products.

Safety Profile

Moderately toxic by intraperitoneal route. A human skin irritant. Combustible when exposed to heat or flame; can react with oxidzing materials. Some spontaneous heating. To fight fire, use CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes

Safety

Olive oil is used widely as an edible oil and in food preparations and products such as cooking oils and salad dressings. It is used in cosmetics and topical pharmaceutical formulations. Olive oil is generally regarded as a relatively nonirritant and nontoxic material when used as an excipient. Olive oil is a demulcent and has mild laxative properties when taken orally. It has been used in topical formulations as an emollient and to sooth inflamed skin; to soften the skin and crusts in eczema; in massage oils; and to soften earwax. There have been isolated reports that olive oil may cause a reaction in hypersensitive individuals. However, these incidences are relatively uncommon.Olive oil is an infrequent sensitizer and does not appear to be a significant allergen in the USA, possibly due to the development of oral tolerance.

storage

When cooled, olive oil becomes cloudy at approximately 10°C, and becomes a butterlike mass at 0°C. Olive oil should be stored in a cool, dry place in a tight, wellfilled container, protected from light. For refined oil intended for use in the manufacture of parenteral dosage forms, the PhEur 6.2 requires that the bulk oil be stored under an inert gas.

Incompatibilities

Olive oil may be saponified by alkali hydroxides. As it contains a high proportion of unsaturated fatty acids, olive oil is prone to oxidation and is incompatible with oxidizing agents.

Regulatory Status

Olive oil is an edible oil. Included in the FDA Inactive Ingredients Database (oral capsules and solution; topical solutions). Included in nonparenteral medicines licensed in Europe. Included in the Canadian List of Acceptable Non-medicinal Ingredients. For nontopical uses, refined olive oil is generally preferred.

Synthetic route

ethanol (64-17-5) + olive oil → olive oil fatty acids, ethyl esters + glycerol (56-81-5)

Conditions	Yield
Fe2Zn3(CN)10 at 150 - 170℃; under 7500.75 Torr; Product distribution / selectivity;

hydroxytyrosol (10597-60-1) + olive oil → palmitic acid-3,4-dihydroxyphenylethyl ester + 2-(3',4'-dihydroxyphenyl)ethyl linoleate + 2-(3,4-dihydroxyphenyl)-ethyl oleate

Conditions	Yield
sulfuric acid

methanol (67-56-1) + olive oil → octadec-9-enoic acid methyl ester (112-62-9) + linoleic acid methyl ester (2462-85-3, 2566-97-4, 20221-26-5, 20221-27-6, 112-63-0) + glycerol (56-81-5)

Conditions	Yield
With sodium hydroxide at 40 - 45℃; for 6h; Product distribution / selectivity;

1-butylene (106-98-9) + olive oil → methyl 9-decenoate (25601-41-6)

Conditions	Yield
[1,3-bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(O-isopropoxyphenylmethylene)ruthenium In dichloromethane at 60℃; under 3620.13 Torr; for 4h; Product distribution / selectivity;

olive oil → olive oil, ozonized

Conditions	Yield
With ozone

Downstream Products

• 25601-41-6 methyl 9-decenoate 
• 112-62-9 octadec-9-enoic acid methyl ester 
• 2462-85-3 linoleic acid methyl ester 
• 56-81-5 glycerol