800409-01-2Relevant articles and documents
Synthesis of anti-tumour phosphatidylinositol analogues from glucose by the use of ring-closing olefin metathesis
Andresen, Thomas L.,Skytte, Dorthe M.,Madsen, Robert
, p. 2951 - 2957 (2004)
A divergent strategy is described for synthesis of the novel phosphatidylinositols 1-3. The synthetic approach commences from benzyl-protected methyl 6-iodo-6-deoxy-α-D-glucopyranoside, which undergoes zinc-mediated reductive fragmentation followed by vin