162792-24-7

Upstream product

• 132662-66-9 1D-5,6-di-O-benzoyl-4-O-benzyl-3-deoxy-1,2-O-isopropylidene-myo-inositol 
• 148888-40-8 1D-4-O-benzyl-3-deoxy-1,2-O-isopropylidene-myo-inositol 
• 100-39-0 benzyl bromide 
• 162792-22-5 C₃₆H₄₀O₆ 
• 162792-21-4 (1R,2R,3R,4S,5R)-3,4,5-Tris-benzyloxy-2-methoxymethoxy-cyclohexanol 
• 162792-19-0 (3aR,4R,5S,6R,7aR)-4,5,6-Tris-benzyloxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxole 
• 162792-20-3 (1R,2R,3S,4S,5R)-3,4,5-Tris-benzyloxy-cyclohexane-1,2-diol 
• 800409-01-2 1D-2,4,5,6-tetra-O-benzyl-3-deoxy-1-O-p-methoxybenzyl-myo-inositol 
• 800409-00-1 1D-2,3-anhydro-4,5,6-tri-O-benzyl-1-O-p-methoxybenzyl-myo-inositol 
• 498554-88-4 1D-4,5,6-tri-O-benzyl-3-deoxy-1-O-p-methoxybenzyl-myo-inositol 
• 128753-68-4 (benzyloxy)chloro(diisopropylamino)phosphane 
• 162792-23-6 1D-2,4,5,6-tetra-O-benzyl-3-deoxy-myo-inositol 
• 108549-21-9 benzyl-N,N,N',N'-tetraisopropylphosphorodiamidite 

Downstream Products

• 1054787-11-9 Phosphoric acid benzyl ester (R)-2-benzyloxy-3-hexadecyloxy-propyl ester (1R,2R,3S,4R,6R)-2,3,4,6-tetrakis-benzyloxy-cyclohexyl ester 
• 162792-27-0 1D-3-deoxyphosphatidylinositol 
• 162792-26-9 Hexadecanoic acid (R)-2-[benzyloxy-((1R,2R,3S,4R,6R)-2,3,4,6-tetrakis-benzyloxy-cyclohexyloxy)-phosphoryloxy]-1-hexadecanoyloxymethyl-ethyl ester 
• 253440-96-9 Phosphoric acid benzyl ester (R)-2-methoxy-3-octadecyloxy-propyl ester (1R,2R,3S,4R,6R)-2,3,4,6-tetrakis-benzyloxy-cyclohexyl ester 
• 253440-95-8 3-deoxy PI ether lipid 
• 162792-25-8 Hexadecanoic acid (R)-2-[benzyloxy-((1R,2R,3S,4R,6R)-2,3,4,6-tetrakis-benzyloxy-cyclohexyloxy)-phosphanyloxy]-1-hexadecanoyloxymethyl-ethyl ester 

Relevant academic research and scientific papers

3-deoxy-3-substituted-D-myo-inositol imidazolyl ether lipid phosphates and carbonate as inhibitors of the phosphatidylinositol 3-kinase pathway and cancer cell growth

3-Modified D-myo-inositol imidazolyl ether lipid phosphates and a carbonate were synthesized and evaluated as inhibitors of PI3-K and Akt. These data are presented along with IC50 values for the inhibition of the growth of three cancer cell lines.

Synthesis of anti-tumour phosphatidylinositol analogues from glucose by the use of ring-closing olefin metathesis

A divergent strategy is described for synthesis of the novel phosphatidylinositols 1-3. The synthetic approach commences from benzyl-protected methyl 6-iodo-6-deoxy-α-D-glucopyranoside, which undergoes zinc-mediated reductive fragmentation followed by vin

Inhibitors of phosphatidyl myo-inositol cycle

The present invention relates to the preparation and biological activity of 3-deoxy-Dmyo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth. The compounds of the present invention are useful as anti-tumor 5 agents which effectively inhibit the growth of mammalian cells.

Synthesis of 1D-3-deoxy- and -2,3-dideoxyphosphatidylinositol

Both 1D-3-deoxy- and -2,3-dideoxyphosphatidylinositol (3 and 18) were synthesized using the regioisomeric mixture of viburnitol 1,2:4,5- and 1,2:5,6- diacetonides as starting material. Selective acidic hydrolysis and subsequent benzylation or deoxygenatio