80120-77-0

Upstream product

• 2861-23-6 4-Hydroxy-4-(3-cyclohexen-1-yl)-2-butanon 
• 100-50-5 3-Cyclohexene-1-carboxaldehyde 
• 23847-20-3 4-(but-3-en-1-yl)cyclohex-1-ene 
• 72581-32-9 cyclohex-3-enylmethanol 
• 92864-78-3 cyclohex-3-en-1-ylmethyl 4-methylbenzenesulfonate 

Downstream Products

• 75091-85-9 E,E-5-(3-cyclohexenyl)-3-methyl-2,4-pentadienoic acid 
• 80120-89-4 (2E,4E)-5-Cyclohex-3-enyl-3-methyl-penta-2,4-dienoic acid methyl ester 
• 80120-92-9 (2E,4E)-5-Cyclohex-3-enyl-3-methyl-penta-2,4-dienoic acid ethyl ester 

Relevant academic research and scientific papers

Terminal olefins to linear α,β-unsaturated ketones: Pd(II)/hypervalent iodine co-catalyzed wacker oxidation-dehydrogenation

Development of a mild (35 C, no Bronsted acids) tandem Wacker oxidation-dehydrogenation of terminal olefins was accomplished using palladium(II) and hypervalent iodine co-catalysis. The reaction affords linear aryl and alkyl α,β-unsaturated ketones directly from readily available terminal olefins in good yields (average 75% per step) with excellent functional group tolerance and chemo- and stereoselectivities. The hypervalent iodine co-catalyst was found to be critical for dehydrogenation but was not effective as a stoichiometric oxidant.

SYNTHESIS OF SOME ANALOGS OF ABSCISIC ACID FROM 3-CYCLOHEXENE-1-CARBALDEHYDE AND ITS METHYL HOMOLOGS

The E,E and Z,E isomers of 5-substituted 3-methyl-2,4-pentanedioic acids were synthesized from 3-cyclohexene-1-carbaldehyde and its methyl homologs.The possibilities of their production by the Reformatsky and Wittig reactions or by condensation of substituted 3-cyclohexene-1-carbaldehydes with diethyl β-methylglutaconate were investigated.It was shown that the last path makes it possible to obtain the Z,E isomers preferentially.