801281-99-2

Basic information

• Product Name: 2-(N-Boc)amino-6-methoxyfluorobenzene
• Synonyms: 2-(N-Boc)amino-6-methoxyfluorobenzene
• CAS NO: 801281-99-2
• Molecular Formula: C₁₂H₁₆FNO₃
• Molecular Weight: 0
• Mol File: 801281-99-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(N-Boc)amino-6-methoxyfluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-Boc)amino-6-methoxyfluorobenzene(801281-99-2)
• EPA Substance Registry System: 2-(N-Boc)amino-6-methoxyfluorobenzene(801281-99-2)

Safety Data

• Hazardous Substances Data: 801281-99-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16FNO3/c1-12(2,3)17-11(15)14-8-6-5-7-9(16-4)10(8)13/h5-7H,1-4H3,(H,14,15)

Upstream product

• 137654-20-7 2-fluoro-3-methoxybenzoic acid 
• 75-65-0 tert-butyl alcohol 
• 801282-00-8 2-fluoro-3-methoxyaniline 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1057720-39-4 tert-butyl N-[6-bromo-2-fluoro-3-methoxyphenyl]carbamate 
• 1357176-75-0 2-fluoro-3-methoxyaniline hydrochloride 
• 1398045-45-8 4-{4-[7-(4-cyano-2-fluoro-3-methoxy-phenyl)-8-oxo-6-thioxo-5,7-diaza-spiro[3.4]oct-5-yl]-phenyl}-2,2,N-trimethyl-butyramide 
• 1398045-39-0 4-{4-[3-(4-cyano-2-fluoro-3-methoxy-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide 
• 1398045-35-6 3-fluoro-4-(3-{4-[3-(1H-imidazol-2-yl)-propyl]-phenyl}-4,4-dimethyl-5-oxo-2-thioxo-imidazolidin-1-yl)-2-methoxy-benzonitrile 
• 1398045-19-6 4-{4-[3-(4-cyano-2-fluoro-3-methoxy-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-N,N-dimethyl-butyramide 
• 1272719-22-8 C₈H₇FN₂O 
• 1272719-21-7 C₁₀H₉FN₂O₂ 
• 1272719-20-6 C₉H₉BrFNO₂ 
• 1272719-19-3 C₇H₇BrFNO 
• 1272719-18-2 4-(4,4-dimethyl-5-oxo-2-thioxo-3-p-cyanophenyl-imidazolidin-1-yl)-3-fluoro-2-methoxy-benzonitrile 
• 1272719-12-6 3-fluoro-4-[3-(3-fluoro-4-methyl-phenyl)-4,4-dimethyl-5-oxo-2-thioxo-imidazolidin-1-yl]-2-methoxy-benzonitrile 
• 1272719-11-5 4-(4,4-dimethyl-5-oxo-2-thioxo-3-p-tolyl-imidazolidin-1-yl)-3-fluoro-2-methoxy-benzonitrile 
• 1272719-10-4 4-[3-(4-cyano-2-fluoro-3-methoxy-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-2-fluoro-N-methyl-benzamide 

Relevant articles and documents

ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF

Disclosed are substituted thioimidazolidinone compounds and pharmaceutical compositions comprising such compounds. The compounds and compositions can be used for treatment of androgen receptor-associated diseases or disorders, such as prostate cancer, benign prostatic hypertrophy, male hair loss and hypertrichosis.

ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF

The present invention relates to novel substituted thioimidazolidinone compounds and pharmaceutical compositions comprising such compounds for treatment of androgen receptor-associated diseases or disorders, such as prostate cancer, benign prostatic hypertrophy, male hair loss, muscle loss, acne and hirsutism.

HEPATITIS C INHIBITOR COMPOUNDS

Compounds of formula (I): wherein B, X, R3, L0, L1, L2, R2, R1 and RC are defined herein. The compounds are useful as inhibitors of HCV NS3 protease for the treatment of hepatitis C viral infection.