80194-83-8

Usage

Uses

Used in Chemical Research:
2-Chloro-N-phenyl-isonicotinamide is utilized as a research compound for studying its chemical interactions and reactivity in various environments. Its unique molecular structure allows scientists to explore its potential in different chemical reactions and processes.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2-Chloro-N-phenyl-isonicotinamide is used as a starting material or intermediate in the synthesis of various drug candidates. Its chemical properties may contribute to the development of new therapeutic agents, particularly in the area of medicinal chemistry.
Used in Material Science:
2-Chloro-N-phenyl-isonicotinamide may also find applications in material science, where its unique properties could be harnessed to create new materials with specific characteristics, such as improved stability or reactivity.

Upstream product

• 55-22-1 pyridine-4-carboxylic acid 
• 14254-57-0 4-(chlorocarbonyl)pyridine 
• 65287-34-5 2-chloropyridine-4-carbonyl chloride 
• 62-53-3 aniline 
• 6313-54-8 2-chloroisonicotinic acid, 
• 201230-82-2 carbon monoxide 
• 153034-91-4 2-chloro-3,4-diiodopyridine 
• 3034-31-9 N-phenylisonicotinamide 
• 14178-44-0 isonicotinanilide-1-oxide 

Downstream Products

• 133928-72-0 2-chloro-3-trimethylsilylisonicotinanilide 
• 133928-67-3 C₁₂H₈⁽²⁾HClN₂O 
• 126798-21-8 2-methoxy-N-phenylisonicotinamide 
• 1027272-37-2 3-Benzylsulfanyl-2-chloro-N-phenyl-isonicotinamide 
• 1027228-29-0 2-Chloro-N-phenyl-3-phenylmethanesulfinyl-isonicotinamide 
• 126798-31-0 3-(p-methoxyphenyl)-furo<3,4-c>pyridine-1,4(3H,5H)-dione 
• 126798-26-3 4-methoxy-3-(p-methoxyphenyl)-furo<3,4-c>pyridine-1(3H)-one 
• 133928-64-0 2-chloro-3,N-dimethyl-N-phenyl-isonicotinamide 
• 1522465-04-8 2-chloro-5-(5-methylthiophen-2-yl)-N-phenylisonicotinamide 
• 1572515-59-3 2-(benzylthio)-N-phenyl-isonicotinamide 
• 1572510-25-8 C₁₈H₂₁N₃O₃S 
• 133930-00-4 4-chloro-3-(p-methoxyphenyl)-furo<3,4-c>pyridine-1(3H)-one 
• 133928-71-9 4-chloro-3-hydroxy-2-phenyl-pyrrolo<3,4-c>pyridine-1(3H)-one 

Relevant academic research and scientific papers

Heterocyclic-substituted nitrogen-containing six-membered heterocyclic derivative and preparation method and medical application thereof

The invention relates to a heterocyclic-substituted nitrogen-containing six-membered heterocyclic derivative, a preparation method thereof and application of the heterocyclic-substituted nitrogen-containing six-membered heterocyclic derivative as a PD-1/PD-L1 inhibitor. Specifically, the invention discloses a compound shown as a formula (I) or a pharmaceutically acceptable salt, a deuterated compound, a stereoisomer, a solvate and a prodrug thereof, and a preparation method and application of the compounds, and the definition of each group in the formula is detailed in the description and claims.

Palladium-catalysed aminocarbonylation of diiodopyridines

The aminocarbonylation of 2,5- and 2,3-diiodopyridine, as well as 2-chloro-3,4-diiodopyridine with carbon monoxide and various primary and secondary amines was carried out using palladium-catalysed aminocarbonylation. The formation of the products contain

SUBSTITUTED BENZENE COMPOUNDS

The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

DIAZABICYCLONONENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS

The invention relates to novel derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, p

DIAZABICYCLONONENE AND TETRAHYDROPYRIDINE DERIVATIVES AS RENIN INHIBITORS

The invention relates to novel bicyclic derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the com

DIAZABICYCLONONENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS

The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I), wherein Z is 0 or 1, one of m, n is 0 and the other is 1, and their use as inhibitors of renin.

DIAZABICYCLONONENE AND TETRAHYDROPYRIDINE DERIVATIVES WITH A NEW SIDE-CHAIN

The invention relates to novel bicyclic derivatives, and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the co

TETRAHYDROPYRIDINE DERIVATIVES

The invention relates to novel tetrahydropyridine derivatives and use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin. (I) wherein X and Y represent independently hydrogen, fluorine or a methyl group; X and Y do not represent both hydrogen at the same time or X and Y may together form a cyclopropyl ring; W represents a phenyl or a heteroaryl, the heteroaryl ring being a six-membered and non-fused ring, the phenyl ring and the heteroaryl are substituted with V in position 3 or 4; A and B independently represent-O-;-S-;-SO-or-SO2-; U represents aryl or heteroaryl; T represents-CONR1-;-(CH2)pOCO-;-(CH2)pN(R1)CO-;-(CH2)p N(R1)SO2-;-COO-;-(CH2)pOCONR1-or-(CH2)pN(R2)CONR1-; R1 and R2 independently respresent hydrogen; lower alkyl; lower alkenyl; lower alkynil; cycloalkyl; aryl-lower alkyl, heteroaryl-lower alkyl or cycloalkyl-lower alkyl; Q represents lower alkylene or lower alkenylene; M represents hydrogen; cycloalkyl; aryl; heterocyclyl or heteroaryl:

HIV protease inhibitors

HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

HIV protease inhibitors

HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.