80200-09-5

Usage

General Description

1-(4-hydroxybenzyl)pyrazole is a chemical compound with the molecular formula C12H11N3O. It is a pyrazole derivative with a hydroxybenzyl group attached. 1-(4-hydroxybenzyl)pyrazole has been reported to have potential therapeutic effects, including antitumor and anti-inflammatory activities. It has also been studied for its possible role in regulating the production of the stress hormone cortisol. Its structure and properties make it a promising candidate for further research and development as a potential pharmaceutical agent for various medical applications.

InChI:InChI=1/C10H10N2O/c13-10-4-2-9(3-5-10)8-12-7-1-6-11-12/h1-7,13H,8H2

Upstream product

• 288-13-1 NH-pyrazole 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 142335-61-3 4-((1H-pyrazol-1-yl)methyl)aniline 
• 110525-57-0 1-(4-nitrobenzyl)-1H-pyrazole 
• 100-14-1 4-nitrobenzyl chloride 

Downstream Products

• 142335-62-4 2-(4-Pyrazol-1-ylmethyl-phenoxy)-propionic acid ethyl ester 
• 173528-79-5 3-[4-(1-pyrazolyl)methylphenoxy]propyl bromide 
• 88670-66-0 1-isopropylamino-3-[4-[(1-pyrazolyl)methyl]phenoxy]-2-propanol 

Relevant academic research and scientific papers

Microwave-Assisted Generation and Capture by Azoles of ortho-Quinone Methide Intermediates under Aqueous Conditions

An efficient activator-free protocol for the coupling of o-hydroxybenzyl alcohols and azoles in water has been developed. This C–N bond-formation process is supposed to proceed through an ortho-quinone methide intermediate. A broad range of o-hydroxybenzy

Ether compounds, their use, and intermediates for use in their production

There are disclosed novel ether compounds of the general formula: STR1 wherein R1 is halogen; A is a group of the general formula Q-1: --CH(R2)--(CH2)m --CH (R3)--N(R4)--C(=Y)--X--R5/

Structure-activity studies on a 1,2,3-triazole derivative, a potent in vitro inhibitor of prostaglandin synthesis: The role of the heterocyclic ring

This paper reports further structural modifications concerning the 1,2,3- triazole ring of the compound A, an effective in vitro inhibitor of prostaglandin synthesis. The introduction of different heterocyclic rings provided further information about of t

β1-Selective Adrenoceptor Antagonists. 3. 4-Azolyl-Linked Phenoxypropanolamines

A series of 4-substituted phenoxypropanolamines has been prepared and examined for β-adrenoceptor activity.The 4-substituents, di- and triazole ring systems connected to the phenoxy ring by different length chains, were chosen as a means of introducing ca