80226-63-7

Upstream product

• 55653-49-1 benzyl 2-aminobutanoate 
• 100-51-6 benzyl alcohol 
• 95656-92-1 benzyl (S)-2-((tert-butoxycarbonyl)amino)butanoate 

Downstream Products

• 1259396-54-7 (S)-2-ethylaminobutanoic acid benzyl ester 
• 1259396-68-3 (S)-2-((tert-butoxycarbonylmethyl)ethylamino)butanoic acid benzyl ester 
• 1532523-83-3 C₂₈H₃₂N₃O₁₀P 

Relevant academic research and scientific papers

NOVEL THIOPHENECARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

The object of the present invention is to provide a compound having a glucokinase-activating effect. A pharmaceutical composition comprising a compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient: wherein X means a nitrogen atom or CR6, wherein R6 means a hydrogen atom or a halogen atom; R1 means a hydrogen atom, a C1-C6 alkyl group, a C1-C6 alkoxy group or a C1-C6 alkylthio group; R2 means a hydrogen atom or a fluorine atom; R3 means a hydrogen atom or a C1-C6 alkyl group; and one of R4 and R5 means a hydrogen atom or a C1-C6 alkyl group, and the other means a C1-C6 alkylenecarboxylic acid, a C1-C6 alkylsulfonyl group, a C1-C6 alkylcarbonyl group, or CONH2.