95656-92-1

Basic information

• Product Name: Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, phenylmethyl ester, (S)-
• CAS NO: 95656-92-1
• Molecular Formula: C16H23NO4
• Molecular Weight: 293.363
• Mol File: 95656-92-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, phenylmethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, phenylmethyl ester, (S)-(95656-92-1)
• EPA Substance Registry System: Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, phenylmethyl ester, (S)-(95656-92-1)

Safety Data

• Hazardous Substances Data: 95656-92-1(Hazardous Substances Data)

Upstream product

• 24608-52-4 tert-butyl chloroformate 
• 34306-42-8 Boc-Abu 
• 100-39-0 benzyl bromide 
• 30924-93-7 Boc-Glu-OBn 
• 124-41-4 sodium methylate 
• 109276-71-3 (S)-2-tert-Butoxycarbonylamino-pentanedioic acid 1-benzyl ester 5-(2-thioxo-2H-pyridin-1-yl) ester 

Downstream Products

• 80226-63-7 (S)-2-amino-butyric acid benzyl ester 
• 1259396-68-3 (S)-2-((tert-butoxycarbonylmethyl)ethylamino)butanoic acid benzyl ester 

Relevant articles and documents

A General Organocatalytic System for Electron Donor-Acceptor Complex Photoactivation and Its Use in Radical Processes

We report herein a modular class of organic catalysts that, acting as donors, can readily form photoactive electron donor-acceptor (EDA) complexes with a variety of radical precursors. Excitation with visible light generates open-shell intermediates under mild conditions, including nonstabilized carbon radicals and nitrogen-centered radicals. The modular nature of the commercially available xanthogenate and dithiocarbamate anion organocatalysts offers a versatile EDA complex catalytic platform for developing mechanistically distinct radical reactions, encompassing redox-neutral and net-reductive processes. Mechanistic investigations, by means of quantum yield determination, established that a closed catalytic cycle is operational for all of the developed radical processes, highlighting the ability of the organic catalysts to turn over and iteratively drive every catalytic cycle. We also demonstrate how the catalysts' stability and the method's high functional group tolerance could be advantageous for the direct radical functionalization of abundant functional groups, including aliphatic carboxylic acids and amines, and for applications in the late-stage elaboration of biorelevant compounds and enantioselective radical catalysis.

NOVEL THIOPHENECARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

The object of the present invention is to provide a compound having a glucokinase-activating effect. A pharmaceutical composition comprising a compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient: wherein X means a nitrogen atom or CR6, wherein R6 means a hydrogen atom or a halogen atom; R1 means a hydrogen atom, a C1-C6 alkyl group, a C1-C6 alkoxy group or a C1-C6 alkylthio group; R2 means a hydrogen atom or a fluorine atom; R3 means a hydrogen atom or a C1-C6 alkyl group; and one of R4 and R5 means a hydrogen atom or a C1-C6 alkyl group, and the other means a C1-C6 alkylenecarboxylic acid, a C1-C6 alkylsulfonyl group, a C1-C6 alkylcarbonyl group, or CONH2.

HOMOLYTIC DECARBOXYLATION OF GLUTAMATE ANALOGUES

The homolytic decarboxylation of a 3-cyclopropylglutamate derivative yields some rearrangement product whereas that of a 3-fluoroglutamate derivative yields the decarboxylation product without elimination.These results are discussed in relationship with t