80228-01-9

Upstream product

• 673-41-6 p-chlorobenzenediazonium tetrafluoroborate 
• 558-17-8 tert-Butyl iodide 
• 53486-30-9 4-chlorobenzenediazonium sulfate 
• 100-00-5 4-chlorobenzonitrile 
• 75-64-9 tert-butylamine 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 136412-82-3 N-tert-Butyl-N'-(4-chloro-phenyl)-diazene N-oxide 

Relevant academic research and scientific papers

NEW GENERAL AND CONVENIENT SOURCES OF ALKIL RADICALS, USEFUL FOR SELECTIVE SYNTHESES

Alkyl radicals are obtained from alkyl icdides under very simple conditions and with cheap reagents: i) H2O2 and DMSO; ii) H2O2 and acetone; iii) t-BuOOH.The alkyl radicals can be utilized for selective syntheses, mainly selective formation of carbon-carb

Synthetic Route to Phenyl Diazenes and Pyridazinium Salts from Phenylazosulfonates

The synthesis of pyridazinium salts was achieved from readily available phenylazosulfonates in a single reaction step. The reaction proceeds via the formation of short-lived phenyldiazenes, which-owing to the strongly acidic conditions-are partially proto

Polar Effects in Reactions of Carbon-Centered Radicals with Diazonium Salts: Free-Radical Diazocoupling

Carbon-centered radicals react with diazonium salts by addition, leading under reductive conditions to azo derivatives (free-radical diazocoupling), or by electron-transfer in chain processes.The reaction is highly sensitive to polar effects and it has been investigated by three different processes: (i) alkyl radicals, generated from alkyl iodides, H2O2, Fe(II) salt, and DMSO, have been utilized to develop a new general synthesis of alkylarylazo compounds; (ii) the reaction of aryl radicals with diazonium salts in the presence of Ti(III) or Fe(II) salts has been investigated, also in relation to the fact that the reaction products (azoarenes and biaryls) are often detected as side products in classical organic reactions of diazonium salts, catalyzed by Cu(I) salts, such as the Sandmeyer, Meerwein, and Pschorr reactions; (iii) adducts from addition of aryl radicals to vinyl acetate or vinyl ether react with diazonium salts either by diazocoupling reaction or by electron-transfer; a general synthesis of arylazo compounds has been developed.

SYNTHESIS OF 1-TERT-BUTYL-2-ARYLDIAZENE-2-OXIDES BY REACTION OF t-BuNHMgBr WITH NITROBENZENES

A new method has been developed for the synthesis of alkylaryldiazene oxides by the reactions of t-BuNHMgBr with nitrobenzenes.The cis-azoxy compound 1-tert-butyl-2-(2-chlorophenyl)diazene-2-oxide, which irreversibly isomerizes to the trans isomer upon he

NEW GENERAL AND CONVENIENT SOURCES OF ALKYL RADICALS, USEFUL FOR SELECTIVE SYNTHESES

Alkyl radicals are obtained from alkyl iodides under very simple conditions and with cheap reagents: i) H2O2 and DMSO; ii) H2O2 and acetone; iii) t-BuOOH.The alkyl radicals can be utilized for selective syntheses, mainly selective formation of carbon-carb