80244-96-8

Basic information

• Product Name: 5-O-acetyl-1,2-O-(1-methylethylidene)pentofuranose
• CAS NO: 80244-96-8
• Molecular Formula: C₁₀H₁₆O₆
• Molecular Weight: 232.2304
• Mol File: 80244-96-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 340.5°C at 760 mmHg
• Flash Point: 130.4°C
• Density: 1.228g/cm³
• Vapor Pressure: 5.66E-06mmHg at 25°C
• Refractive Index: 1.468
• CAS DataBase Reference: 5-O-acetyl-1,2-O-(1-methylethylidene)pentofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 5-O-acetyl-1,2-O-(1-methylethylidene)pentofuranose(80244-96-8)
• EPA Substance Registry System: 5-O-acetyl-1,2-O-(1-methylethylidene)pentofuranose(80244-96-8)

Safety Data

• Hazardous Substances Data: 80244-96-8(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 141-78-6 ethyl acetate 
• 75-36-5 acetyl chloride 
• 7137-32-8 acetic pivalic mixed anhydride 
• 59940-64-6 3-O-Acetyl-1,2-O-isopropyliden-α-D-xylofuranose 
• 126308-96-1 Acetic acid (3aR,5R,6S,6aR)-6-(3,4-dimethoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl ester 
• 42927-45-7 3,5,6-tri-O-acetyl-1,2-O-isopropylidene-α-D-xylofuranose 

Downstream Products

• 1187322-37-7 C₂₅H₃₄N₂O₉ 
• 1187322-28-6 C₂₄H₃₄N₂O₈ 
• 1187322-26-4 C₂₂H₃₂N₂O₆ 
• 1187322-32-2 C₂₂H₃₀N₂O₅ 
• 37077-81-9 1,2-isopropylidene-α-D-ribofuranose 
• 97551-74-1 3-<(3S,5S)-7-oxo-1-aza-4-oxabicyclo<3.2.0>hept-3-yl>-N-(benzyloxycarbonyl)-L-alanine diphenylmethyl ester 
• 97590-61-9 3-<(3S,5R)-7-oxo-1-aza-4-oxabicyclo<3.2.0>hept-3-yl>-N-(benzyloxycarbonyl)-L-alanine diphenylmethyl ester 
• 97569-85-2 N-(benzyloxycarbonyl)-5-bromo-4-(4-oxo-2-azetidinyloxy)-D-threo-L-norvaline diphenylmethyl ester 
• 97551-71-8 N-(benzyloxycarbonyl)-4,5-bis<<(4-chlorophenyl)sulfonyl>oxy>-4-D-threo-L-norvaline diphenylmethyl ester 
• 97569-84-1 N-(benzyloxycarbonyl)-5-<<(4-chlorophenyl)sulfonyl>oxy>-4-(4-oxo-2-azetidinyloxy)-D-threo-L-norvaline diphenylmethyl ester 
• 97551-72-9 N-(benzyloxycarbonyl)-5-<<(4-chlorophenyl)sulfonyl>oxy>-4-hydroxy-D-threo-L-norvaline diphenylmethyl ester 
• 97551-75-2 L-allo-1-(benzyloxycarbonyl)-4-((4-ooazetidin-2-yl)oxy)proline diphenylmethyl ester 
• 97551-73-0 2-<(benzyloxycarbonyl)amino>-5-O-<(4-chlorophenyl)sulfonyl>-2,3-dideoxy-D-threo-pentafuranonic acid γ-lactone 
• 97551-70-7 N-(benzyloxycarbonyl)-4,5-dihydroxy-D-threo-L-norvaline diphenylmethyl ester 

Relevant articles and documents

Application of ortho esterification under kinetically controlled conditions to the selective acylation in the D-gluco-, D-ribo- and D-xylo-furanose series

The ortho esterification of various glucofuranoses in the D-ribo, D-xylo and D-gluco series under kinetic control was obtained through the action of 1,1-dimethoxyethene (a ketene acetal) on the monosaccharide using mild acid conditions. The selective hydrolysis of the methoxyethylidene derivatives thus obtained, gave access to α-hydroxy acetates which are useful synthetic intermediates.

METHOD OF PREPARING DEOXYRIBOFURANOSE COMPOUNDS

The invention relates to methods for making deoxyribofuranose compounds such as compound (2) which are useful intermediates in the preparation of pharmaceutical compounds such as 5-amino-3-(2'-O-acetyl-3'-deoxy-β-D-ribofuranosyl)-3H- thiazolo[4,5-d]pyrimidin-2-one and the like.

Thermodynamic and kinetic considerations in the chemoselective O-acylation by mixed anhydrides. A semiempirical MO approach

A simple methodology to achieve high chemoselective O-acylation of primary hydroxy groups, in the presence of secondary ones, was performed by means of the quick generation of a mixed anhydride using mild and inexpensive conditions. Steric and electronic