80258-49-7

Upstream product

• 1207-69-8 9-Chloroacridine 
• 86955-82-0 4-amino-3,5-dimethylmethanesulfonanilide 
• 86955-80-8 4-<(benzyloxycarbonyl)amino>-3,5-dimethylmethanesulfonanilide 
• 86955-76-2 N-(benzyloxycarbonyl)-2,6-dimethyl-4-nitroaniline 
• 86955-78-4 N-(benzyloxycarbonyl)-2,6-dimethyl-4-aminoaniline 
• 67083-22-1 N-(2,6-dimethyl-4-nitrophenyl)-4-methylbenzenesulfonamide 
• 16947-63-0 2,6-dimethyl-4-nitroaniline 

Relevant academic research and scientific papers

Potential antitumor agents. 39. Anilino ring geometry of amsacrine and derivatives: Relationship to DNA binding and antitumor activity

The clinical antileukemic drug amsacrine and analogues are thought to exert their biological activity by binding tightly but reversibly to DNA, with the acridine chromophore intercalated and the anilino group making additional binding contact in the minor