86955-76-2

Upstream product

• 16947-63-0 2,6-dimethyl-4-nitroaniline 
• 501-53-1 benzyl chloroformate 
• 67083-22-1 N-(2,6-dimethyl-4-nitrophenyl)-4-methylbenzenesulfonamide 

Downstream Products

• 86955-78-4 N-(benzyloxycarbonyl)-2,6-dimethyl-4-aminoaniline 
• 700361-47-3 Rilpivirine hydrochloride 
• 661489-23-2 (2E)-3-(4-amino-3,5-dimethylphenyl)prop-2-enenitrile hydrochloride 
• 86955-80-8 4-<(benzyloxycarbonyl)amino>-3,5-dimethylmethanesulfonanilide 
• 86955-82-0 4-amino-3,5-dimethylmethanesulfonanilide 
• 80258-49-7 N-[4-(Acridin-9-ylamino)-3,5-dimethyl-phenyl]-methanesulfonamide; hydrochloride 

Relevant academic research and scientific papers

RILPIVIRINE PROCESS

Disclosed is process for the preparation of a key Rilpivirine intermediate namely, (E)-4-(2-cyanoethenyl)-2,6-dimethylphenylamine hydrochloride (II) by a process comprising reaction of the tetrafluoroborate salt of the diazonium ion of 2,6-dimethyl-4-amin

Potential antitumor agents. 39. Anilino ring geometry of amsacrine and derivatives: Relationship to DNA binding and antitumor activity

The clinical antileukemic drug amsacrine and analogues are thought to exert their biological activity by binding tightly but reversibly to DNA, with the acridine chromophore intercalated and the anilino group making additional binding contact in the minor