80304-38-7Relevant academic research and scientific papers
Analgesic, antipyretic or anti-inflammatory imidazole compounds
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, (2008/06/13)
New imidazole compounds of the formula STR1 their salts and analgesic, antipyretic and antiinflammatory pharmaceutical composition containing them. New intermediates useful in the preparation of said imidazole compounds. Process for preparing the new imid
Synthesis of 4(5)-Hydroxymethylimidazoles by Hydroxymethylation and Decarboxylation of Imidazole-4(5)-carboxylic Acids
Kim, Choong S.,Lee, Kee J.,Kim, Hong S.,Chae, Yung B.
, p. 1417 - 1418 (2007/10/02)
4(5)-Hydroxymethylimidazoles were prepared by hydroxymethylation and decarboxylation of imidazole-4(5)-carboxylic acid esters.The reaction was simply carried out with aqueous formaldehyde solution in the presence of base.
Process for the production of hydroxymethylimidazoles
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, (2008/06/13)
This invention discloses a process for the production of hydroxymethylimidazoles which comprises reacting imidazolecarboxylic acids, their esters or inorganic salts with a formaldehyde agent in the presence of an alkali in an aqueous medium.
