80309-01-9

Upstream product

• 861067-83-6 1-(1-acetoxy-4-bromo-[2]naphthyl)-ethanone 
• 35085-58-6 1-(1-acetyloxynaphthalen-2-yl)ethanone 
• 828276-32-0 2-bromo-1-(1-acetyloxynaphthalen-2-yl)ethanone 
• 861067-59-6 1-(1-acetoxy-4-bromo-[2]naphthyl)-2-bromo-ethanone 
• 67029-82-7 2-bromo-1-(1-hydroxy-[2]naphthyl)-ethanone 
• 52220-64-1 1-(4-bromo-1-hydroxynaphthalen-2-yl)ethanone 
• 711-79-5 1-hydroxy-2-acetonaphthone 

Downstream Products

• 80308-99-2 5-bromo-2-(p-methoxybenzylidene)-6,7-benzocoumaran-3-one 

Relevant academic research and scientific papers

PdCl2/CuCl2/Bi(OTf)3-promoted Construction of Sulfonyl Dibenzooxabicyclo[3.3.1]nonanes and Arylnaphthalenes via Intramolecular Annulation of Sulfonyl o-Allylarylchromanones

PdCl2/CuCl2/Bi(OTf)3-promoted intramolecular domino annulation of sulfonyl o-allylarylchromanones provides tetracyclic sulfonyl dibenzooxabicyclo[3.3.1]nonanes and bicyclic arylnaphthalenes with good to excellent yields in MeOH at room (25 °C) and refluxing (65 °C) temperature, respectively. The starting sulfonyl o-allylarylchromanones can be easily obtained from the intermolecular cyclocondensation of α-sulfonyl o-hydroxyacetophenones and o-allylbenzaldehydes. The uses of various catalysts and solvent systems are investigated herein for convenient transformation. A plausible mechanism is proposed and discussed. This protocol provides one-pot ring closure via carbon-carbon (C?C) bond formation. (Figure presented.).

Reactivity of 2'-Hydroxy-3',4'-benzochalkone Dibromides

Bromination of 2'-hydroxy-4-methoxy-3',4'-benzochalkone (Ia) with 2 mol of bromine in acetic acid gives 5'-bromo-2'-hydroxy-4-methoxy-3',4'-benzochalkone α,β-dibromide (IIa) which on treatment with hot aq. ethanolic alkali or pyridine does not give the ex