80314-39-2Relevant academic research and scientific papers
ANOMALOUS METALATION BEHAVIOR IN 1,3-OXAZOLES. ALKYLATION OF 2-METHYL-4-CARBOXYOXAZOLES VIA THE CORNFORTH INTERMEDIATE
Meyers, A. I.,Lawson, John P.
, p. 3163 - 3166 (1981)
Metalation of the methyl group in the title compound is accomplished through the open chain Cornforth precursor.This technique is necessary due to the preferred metalation of the 5-H proton in oxazoles.
Dimethyl Aminomalonate: A Useful C-3 Unit in a Mild, Direct Synthesis of Oxazole-4-carboxylates
Shapiro, Rafael
, p. 5759 - 5764 (2007/10/02)
N-Acyl derivatives of the title compound undergo oxidative cyclization upon treatment with N-chlorosuccinimide in DMF to form dimethyl 4,5-dihydro-5-(phenylthio)oxazole-4,4-dicarboxylates 4 which then are decarbomethoxylated with concomitant loss of thiop
