80352-52-9

Usage

Uses

Used in Pharmaceutical Industry:
2-(benzyloxy)-3-chlorobenzaldehyde is utilized as an intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Agrochemical Industry:
2-(benzyloxy)-3-chlorobenzaldehyde serves as an intermediate in the production of agrochemicals, playing a role in the creation of products designed to protect crops and enhance agricultural yields.
Used in Dye Industry:
2-(benzyloxy)-3-chlorobenzaldehyde is employed in the synthesis of dyes, where its chemical structure contributes to the color properties of the final products.
Used in Fragrance Industry:
2-(benzyloxy)-3-chlorobenzaldehyde is used as a component in the production of fragrances and flavors, capitalizing on its aromatic characteristics to create appealing scents and tastes.
Used in Anti-inflammatory Applications:
2-(benzyloxy)-3-chlorobenzaldehyde has been studied for its potential use in anti-inflammatory treatments, suggesting that it may have therapeutic benefits in reducing inflammation.
Used in Anti-tumor Applications:
2-(benzyloxy)-3-chlorobenzaldehyde is also being investigated for its potential role in anti-tumor applications, indicating that it could be a valuable component in the fight against cancer.

Upstream product

• 1927-94-2 3-chlorosalicylaldehyde 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 23363-64-6 chlorflavonin 
• 80352-55-2 3'-chloro-2'-benzyloxy-5,7-dihydroxy-3-methoxyflavone 
• 80352-54-1 2-benzyloxy-3-chlorobenzoic anhydride 
• 80352-56-3 3'-chloro-2'-benzyloxy-5,7,8-trihydroxy-3-methoxyflavone 
• 80352-57-4 3'-chloro-2'-benzyloxy-5-hydroxy-3,7,8-trimethoxyflavone 
• 1344738-19-7 1-[2-({3-[2-(benzyloxy)-3-chlorophenyl][1,2,4]triazolo[4,3-a]pyridin-6-yl}thio)phenyl]methanamine 
• 1344738-17-5 [2-({3-[2-(benzyloxy)-3-chlorophenyl][1,2,4]triazolo[4,3-a]pyridin-6-yl}thio)phenyl]methanol 
• 1344738-14-2 3-[2-(benzyloxy)-3-chlorophenyl]-6-bromo[1,2,4]triazolo[4,3-a]pyridine 
• 876299-08-0 1-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]-3-(2-{[3-(3-chloro-2-hydroxyphenyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]thio}benzyl)urea 
• 1344738-26-6 1-[2-({3-[2-(benzyloxy)-3-chlorophenyl][1,2,4]triazolo[4,3-a]pyridin-6-yl}thio)benzyl]-3-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]urea 
• 1344738-12-0 2-(benzyloxy)-3-chlorobenzaldehyde (5-bromopyridin-2-yl)hydrazone 
• 80352-53-0 2-benzyloxy-3-chlorobenzoic acid 

Relevant academic research and scientific papers

SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN

The present invention relates to sulfamate derivative compounds and a composition for treating and/or alleviating pain containing the sulfamate derivative compounds or a pharmaceutically acceptable salt thereof as an active ingredient. More specifically,

Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary disease

This paper describes the identification and optimization of a novel series of DFG-out binding p38 inhibitors as inhaled agents for the treatment of chronic obstructive pulmonary disease. Structure based drug design and "inhalation by design" principles have been applied to the optimization of the lead series exemplied by compound 1a. Analogues have been designed to be potent and selective for p38, with an emphasis on slow enzyme dissociation kinetics to deliver prolonged lung p38 inhibition. Pharmacokinetic properties were tuned with high intrinsic clearance and low oral bioavailability in mind, to minimize systemic exposure and reduce systemically driven adverse events. High CYP mediated clearance and glucuronidation were targeted to achieve high intrinsic clearance coupled with multiple routes of clearance to minimize drug-drug interactions. Furthermore, pharmaceutical properties such as stability, crystallinity, and solubility were considered to ensure compatibility with a dry powder inhaler. 1ab (PF-03715455) was subsequently identified as a clinical candidate from this series with efficacy and safety profiles confirming its potential as an inhaled agent for the treatment of COPD.

SYNTHESIS OF CHLORFLAVONIN

The synthesis of chlorflavonin, a naturally occurring antifungal antibiotic, is reported.