2-(benzyloxy)-3-chlorobenzaldehyde

Base Information

• Chemical Name: 2-(benzyloxy)-3-chlorobenzaldehyde
• CAS No.: 80352-52-9
• Molecular Formula: C₁₄H₁₁ClO₂
• Molecular Weight: 246.693
• Mol file: 80352-52-9.mol

Synonyms:2-(benzyloxy)-3-chlorobenzaldehyde

Chemical Property of 2-(benzyloxy)-3-chlorobenzaldehyde

Chemical Property:

Purity/Quality:

2-(Benzyloxy)-3-chlorobenzaldehyde 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(benzyloxy)-3-chlorobenzaldehyde

There total 2 articles about 2-(benzyloxy)-3-chlorobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-chlorosalicylaldehyde (1927-94-2) + benzyl bromide (100-39-0) → 2-(benzyloxy)-3-chlorobenzaldehyde (80352-52-9)

Guidance literature:

With potassium carbonate; In acetonitrile; for 4h; Reflux;

Reference yield: 66.6%

3-chlorosalicylaldehyde (1927-94-2) + benzyl chloride (100-44-7) → 2-(benzyloxy)-3-chlorobenzaldehyde (80352-52-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 1h; Heating;

Reference yield: 86.0%

5-bromo-2-hydrazinylpyridine (77992-44-0) + 2-(benzyloxy)-3-chlorobenzaldehyde (80352-52-9) → 2-(benzyloxy)-3-chlorobenzaldehyde (5-bromopyridin-2-yl)hydrazone (1344738-12-0)

Guidance literature:

In ethanol; at 80 ℃; for 0.25h; Inert atmosphere;

DOI:10.1021/jm200677b

upstream raw materials:

3-chlorosalicylaldehyde

benzyl chloride

benzyl bromide

Downstream raw materials:

2-benzyloxy-3-chlorobenzoic acid

chlorflavonin

3'-chloro-2'-benzyloxy-5,7-dihydroxy-3-methoxyflavone

2-benzyloxy-3-chlorobenzoic anhydride