80352-65-4

Basic information

• Product Name: Propanedioic acid, (3-nitro-4-pyridinyl)-, bis(phenylmethyl) ester
• CAS NO: 80352-65-4
• Molecular Formula: C22H18N2O6
• Molecular Weight: 406.395
• Mol File: 80352-65-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, (3-nitro-4-pyridinyl)-, bis(phenylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, (3-nitro-4-pyridinyl)-, bis(phenylmethyl) ester(80352-65-4)
• EPA Substance Registry System: Propanedioic acid, (3-nitro-4-pyridinyl)-, bis(phenylmethyl) ester(80352-65-4)

Safety Data

• Hazardous Substances Data: 80352-65-4(Hazardous Substances Data)

Upstream product

• 15014-25-2 malonic acid dibenzyl ester 
• 13091-23-1 4-chloro-3-nitropyridine 

Downstream Products

• 54415-85-9 6-azaoxindole 
• 847801-90-5 4-(benzyloxycarbomethyl)-3-nitropyridine 

Relevant articles and documents

Substituted indoles as inhibitors of poly (ADP-ribose) polymerase (PARP)

The present invention relates to a series of substituted indole derivatives of the formula I: wherein R, R1, R2, R3, R4, X and Y are as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are inhibitors of poly(adenosine 5′-diphosphate ribose) polymerase (PARP) and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases, including diseases associated with the central nervous system and cardiovascular disorders.