80356-47-4Relevant academic research and scientific papers
4-Hydro-2-quinolones. 192. *relationship of xy structure and analgesic activity of 4-amino-2-oxo-1,2-dihydroquinoline-3-carboxylic acids and their derivatives
Ukrainets,Mospanova,Davidenko,Shishkina
experimental part, p. 1371 - 1379 (2011/10/18)
Some 4-N-R-2-Oxo-1,2-dihydroquinoline-3-carboxylic acids and their derivatives were synthesized as close structural analogs of the highly-active analgesic 4-benzylamino-2-oxo-1,2-dihydroquinoline-carboxylic acid. Pharmacological testing showed that manife
COMPOUNDS, COMPOSITIONS AND METHODS
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Page/Page column 73-74; 35, (2010/11/24)
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
4-Hydroxyquinol-2-ones. 87. Unusual synthesis of 1-R-4-hydroxy-1-oxo-1,2- dihydroquinoline-3-carboxylic acid pyridylamides
Ukrainets,Sidorenko,Slobodzyan,Rybakov,Chernyshev
, p. 1158 - 1166 (2007/10/03)
4-Chloro-2-oxo-1,2-dihydroquinoline-3-carboxylic acids and their esters react with aminopyridines in refluxing DMF to give the corresponding 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid pyridylamides. Their structures were proved by 1
Methods for the Synthesis of 4-Azido-2(1H)-quinolones
Stadlbauer, Wolfgang
, p. 1305 - 1324 (2007/10/02)
4-Hydroxy-2-quinolones 1 are generally found to be converted to the 4-azidocompounds 3 via the 4-chloroquinolones 2, the 4-tosyloxyquinolones 6, or the 4-aminoquinolones 4, respectively.Choice of the reaction conditions and yields depend on the substituen
