80360-24-3 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
The chemical structure describes the arrangement of atoms and the type of chemical bonds between them in the compound.
Explanation
The compound's unique structure and properties make it a target for research and development in the pharmaceutical industry, with the potential to be used in creating new medications.
Explanation
Additional research is required to understand the compound's full potential in treating specific medical conditions and to identify any possible adverse effects.
Explanation
The compound is classified as an organic compound because it contains carbon and hydrogen atoms, along with other elements such as nitrogen, oxygen, and sulfur.
Explanation
These functional groups are responsible for the compound's unique properties and potential applications in the pharmaceutical industry.
Explanation
The molecular weight is the sum of the atomic weights of all the atoms in the molecule, which can be used to calculate the compound's physical properties and reactivity.
Explanation
The compound's solubility in these solvents can be important for its use in pharmaceutical formulations and drug delivery systems.
Explanation
The compound's stability under various conditions can affect its shelf life, storage requirements, and potential applications in drug development.
Explanation
The synthesis method is crucial for producing the compound in a controlled manner, with high purity and yield, for further research and development.
Chemical Structure
A derivative of indole with a phenylsulfonyl group attached to the indole ring and an ethanol group attached to the carbon at position 1.
Potential Pharmaceutical Applications
Development of new drugs for various medical conditions.
Research and Development
Further studies needed to explore potential therapeutic uses and any potential side effects.
Chemical Classification
Organic compound.
Functional Groups
Indole, phenylsulfonyl, and ethanol groups.
Molecular Weight
Approximately 343.41 g/mol.
Solubility
Solubility in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO).
Stability
May be sensitive to light, heat, and moisture.
Syntheses
Can be synthesized through various chemical reactions involving indole and phenylsulfonyl chloride, followed by the addition of an ethanol group.
Check Digit Verification of cas no
The CAS Registry Mumber 80360-24-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,3,6 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 80360-24:
(7*8)+(6*0)+(5*3)+(4*6)+(3*0)+(2*2)+(1*4)=103
103 % 10 = 3
So 80360-24-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H15NO3S/c1-12(18)16-11-13-7-5-6-10-15(13)17(16)21(19,20)14-8-3-2-4-9-14/h2-12,18H,1H3
80360-24-3Relevant articles and documents
A direct lithiation route to 2-acyl-1-(phenylsulfonyl)indoles
Jiang, Jun,Gribble, Gordon W.
, p. 2035 - 2040 (2007/10/03)
2-Acyl-1-(phenylsulfonyl)indoles (3, 7-9) are prepared in 75-84% yield from 1-(phenylsulfonyl)indoles (1, 5) in one operation by treatment of the latter with s-butyllithium followed by inverse quenching of the C-2 lithioindoles with carboxylic acid anhydr
A DIRECTED METALATION ROUTE TO THE ZWITTERIONIC INDOLE ALKALOIDS. SYNTHESIS OF SEMPERVIRINE
Gribble, Gordon W.,Barden, Timothy C.,Johnson, David A.
, p. 3195 - 3202 (2007/10/02)
A synthesis protocol involving beta-lithiation of 2-(2-pyridinyl)indoles(45) and subsequent reaction with bromoacetaldehyde leads to the indoloquinolizine (1) ring system.Application of this methodology to 2-(2-pyridinyl)indole 17, which is prepared via Taylor-Boger triazine Diels-Alder annulation chemistry, affords the zwitterionic indole alkaloid sempervirine (3).
Generation and Reactions of 3-Lithio-1-(phenylsulfonyl)indole
Saulnier, Mark G.,Gribble, Gordon W.
, p. 757 - 761 (2007/10/02)
Treatment of 1-(phenylsulfonyl)-3-iodoindole (6) with 2 equiv of tert-butyllithium (-100 deg C THF) generates essentially quantitatively 3-lithio-1-(phenylsulfonyl)indole (1).Quenching 1 with various electrophiles gives 3-substituted indoles in good yield
