80374-03-4

Basic information

• Product Name: 12α-hydroxypregn-4-en-3-one-20-carboxylic acid methyl ester
• Synonyms: 12α-hydroxypregn-4-en-3-one-20-carboxylic acid methyl ester
• CAS NO: 80374-03-4
• Molecular Weight: 374.521
• Mol File: 80374-03-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 12α-hydroxypregn-4-en-3-one-20-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 12α-hydroxypregn-4-en-3-one-20-carboxylic acid methyl ester(80374-03-4)
• EPA Substance Registry System: 12α-hydroxypregn-4-en-3-one-20-carboxylic acid methyl ester(80374-03-4)

Safety Data

• Hazardous Substances Data: 80374-03-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 302-95-4 sodium cholate 

Relevant articles and documents

MICROBIAL DEGRADATION OF DEOXYCHOLIC ACID BY PSEUDOMONAS sp. NCIB 10590. CHARACTERISATION OF PRODUCTS AND A POSTULATED PATHWAY

Minor products in the microbial degradation of deoxychlolic acid are characterised and a metabolic pathway proposed.In a previous publocation we reported the transformation of deoxycholic acid 1 by Pseudomonas sp.NCIB 10590, in a mineral salts medium, to a mixture of neutral and acidic steroids.The major neutral product, 12β-hydroxyandrosta-1,4-dien-3,17-dione 2 and the major acidic product 12α-hydroxypregna-1,4-dien-3-one-20-carboxylic acid 9 were identified.We now report the structures of the minor products and propose a metabolic pathway.