8038-99-1

Basic information

• Product Name: Alkohol(C8-C18)ethoxylate mit >2 EO
• CAS NO: 8038-99-1
• Molecular Weight: 0
• Mol File: 8038-99-1.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Alkohol(C8-C18)ethoxylate mit >2 EO(CAS DataBase Reference)
• NIST Chemistry Reference: Alkohol(C8-C18)ethoxylate mit >2 EO(8038-99-1)
• EPA Substance Registry System: Alkohol(C8-C18)ethoxylate mit >2 EO(8038-99-1)

Safety Data

• Hazardous Substances Data: 8038-99-1(Hazardous Substances Data)

Upstream product

• 2615-15-8 pentaethylene glycol 
• 112-82-3 hexadecanyl bromide 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 4860-03-1 1-Chlorohexadecan 
• 6068-28-6 tosylate de n-hexadecyle 
• 107-21-1 ethylene glycol 
• 111-46-6 diethylene glycol 
• 112-60-7 Tetraethylene glycol 
• 903579-54-4 1-(2-{2-[2-(2-hexadecyloxyethoxy)ethoxy]ethoxy}ethoxy)tetrahydropyran 
• 86259-87-2 1-phenyl-2,5,8,11-tetraoxatridecan-13-ol 
• 36653-82-4 1-Hexadecanol 
• 112-92-5 1-octadecanol 
• 112-89-0 1-Bromooctadecane 
• 31081-59-1 1-octadecyl methanesulfonate 

Relevant articles and documents

N4 - hydroxycytidine derivative as well as preparation method and application thereof

The invention relates to N4 - hydroxycytidine derivatives as shown in general formula I. A pharmaceutically acceptable salt, a tautomer thereof, a stereoisomer thereof, a metabolite thereof, a metabolic precursor thereof, or a prodrug thereof, and the substituted N4 - hydroxycytidine derivative structure of the structure of Formula I. The pharmaceutical composition is used for preparing medicaments for treating infections such as SARS-CoV, HBV, HCV, H1N1, Ebola and SARS-CoV - 2, can effectively inhibit influenza viruses and SARS-CoV - 2 viruses, and can have the same result on other RNA viruses. The series of compounds can be applied to preparation of anti RNA virus drugs. The medicine is used for preparing a medicine for treating virus infection and is used for preparing a vaccine adjuvant for treating virus infection.

An N4-hydroxycytoside derivative and its preparation method and use

The present invention provides an N4- hydroxycytidine derivative as shown in formula I, a pharmaceutically acceptable salt thereof, a tautomer thereof, a stereoisomer thereof, a metabolite thereof, a metabolic precursor thereof, or a prodrug thereof: 。 The compounds of the present invention have the following significant advantages: (1) the N4-hydroxycytidine compounds and their derivatives have a highly efficient inhibitory activity of RNA-dependent RNA polymerases of RNA viruses; (2) the N4-hydroxycytoside compounds and their derivatives and pharmaceutical compositions are widely used, can be prepared to treat / prevent SARS-CoV, HBV, HCV, H1N1, Ebola or SARS-CoV-2 virus infection disease drugs.

Liposome Enhanced Detection of Amyloid Protein Aggregates

Thioflavin-T is used to image amyloid aggregates because of the excellent turn-on fluorescence properties, but binding affinities are low. By mounting multiple dye units on the surface of a vesicle, the binding affinity for α-synuclein fibrils is increased by three orders of magnitude, and the optical response is increased. Cooperative interactions of the dye headgroup and lipid with the protein provide a general strategy for the construction of multivalent amyloid probes based on vesicles.