80443-63-6Relevant articles and documents
Method for preparing 2-[2-(4-chlorphenyl)ethyl]-2-(1,1-dimethyl ethyl) ethylene oxide
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Paragraph 0023-0024; 0030-0037, (2019/02/26)
The invention relates to a method for preparing 2-[2-(4-chlorphenyl)ethyl]-2-(1,1-dimethyl ethyl) ethylene oxide. The method comprises the following steps: adding a solvent, a raw material B and alkali into a reactor, and stirring for 0.2-1 hour; dropping 1-(4-chlorphenyl)-4,4-dimethyl-3-pentanone (raw material A) to react, thereby obtaining the 2-[2-(4-chlorphenyl)ethyl]-2-(1,1-dimethyl ethyl) ethylene oxide (formula C). The structural general formula of the raw material B is as shown in the description. In the formula, X is chlorine, bromine or iodine. The raw materials are readily available, the odor is small, the toxicity of reagents and drugs used in the operating process is relatively low, the reaction condition is mild, the time is short, and the odor is smaller than that of commondimethyl sulfide. Meanwhile, when methylbenzene serves as a solvent, the cost is low, the amount of three wastes is small, the content of target products is high, and the method is very suitable for industrial production.