80467-45-4Relevant academic research and scientific papers
Development of an acyl sulfonamide anti-proliferative agent, ly573636 ? na
Yates, Matthew H.,Kallman, Neil J.,Ley, Christopher P.,Wei, Jeffrey N.
, p. 255 - 262 (2009)
The synthesis of 5-bromo-thiophene-2-sulfonic acid 2,4-dichlo- robenzoylamide sodium salt on multikilogram scale is described. The initial clinical supplies were made using carbonyl diimidazole to converge the two fragments. A more efficient acid chloride process has been developed, which also provides better control of impurities and color throughout the synthesis.
Visible-Light-Mediated Late-Stage Sulfonylation of Anilines with Sulfonamides
Chu, Man-Hei,Du, Xian,Li, Yi-Hui,Luo, Yong,Xu, Xiao-Hong,Yuan, Han,Zhen, Jing-Song
supporting information, p. 853 - 858 (2022/02/05)
A visible-light-mediated late-stage sulfonylation of anilines with sulfonamides under simple reaction conditions is presented. Various primary or secondary sulfonamides including several pharmaceuticals were incorporated successfully via N–S bond activati
Some Heterocyclic Sulfonyl Chlorides and Derivatives
Cremlyn, Richard J.,Swinbourne, Fred J.,Yung, Kin-Man
, p. 997 - 1006 (2007/10/02)
The syntheses of 4- and 5-chlorosulfonylfuran-2-carboxylic acid (Ia,IIa), 4-chlorosulfonylfuran-2-carboxamide (Ib), 3,5-dimethylpyrazole and isoxazole-4-sulfonyl chlorides (IIa, IVa) and 2,4-dimethylthiazole-5-sulfonyl chloride (Va) are described.The sulf
