805229-68-9

Usage

Chemical structure

A complex structure containing a spiro ring system, a ketone group, and a hydroxymethyl and methyl substituent.

Molecular weight

192.23 g/mol

Appearance

Unknown, but likely a solid or viscous liquid due to its molecular weight and structure.

Solubility

Unknown, but likely soluble in organic solvents such as ethanol, methanol, or acetone.

Stability

Unknown, but may be sensitive to heat, light, or moisture due to its complex structure and functional groups.

Reactivity

Unknown, but may react with strong acids, bases, or oxidizing agents due to the presence of a ketone group and hydroxymethyl substituent.

Applications

Potential applications in pharmaceuticals due to its antifungal and antibacterial properties. It may also have potential use as a building block in organic synthesis.

Synthesis

Requires careful handling and expertise in organic chemistry for its synthesis and manipulation due to its complex structure.

Safety

Unknown, but caution should be exercised when handling 1,4-Dioxaspiro[4.5]decan-8-one,7-(hydroxymethyl)-7-methyl-(9CI) due to its potential reactivity and unknown safety profile. Appropriate safety measures, such as wearing gloves and using a fume hood, should be taken during synthesis and manipulation.

Upstream product

• 50-00-0 formaldehyd 
• 702-69-2 7-methyl-1,4-dioxa-spiro[4.5]decan-8-one 
• 4746-97-8 cyclohexanedione monoethylene ketal 

Downstream Products

• 1309788-54-2 7-benzyloxymethyl-7-methyl-1,4-dioxaspiro[4.5]decane 
• 1309788-55-3 3-benzyloxymethyl-3-methylcyclohexanone 
• 875929-73-0 [8-allyloxycarbonyloxy-9-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-1,4-dioxa-spiro[4.5]dec-7-en-7-yl]-acetic acid ethyl ester 
• 875929-74-1 [9-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-8-oxo-1,4-dioxa-spiro[4.5]dec-7-yl]-acetic acid ethyl ester 
• 875929-66-1 9-allyl-7-(tert-butyl-diphenyl-silanyloxymethyl)-7-methyl-1,4-dioxa-spiro[4.5]decan-8-one 
• 875929-65-0 7-(tert-butyl-diphenyl-silanyloxymethyl)-7-methyl-1,4-dioxa-spiro[4.5]decan-8-one 

Relevant academic research and scientific papers

INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF

Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as described in the specification.

Total synthesis of (±)-jiadifenin and studies directed to understanding its SAR: Probing mechanistic and stereochemical issues in palladium-mediated allylation of enolate-like structures

The total synthesis of jiadifenin has been accomplished. The synthesis allows us to build an SAR profile which suggests that the jiadifenin skeleton may be less desirable from the standpoint of nominating a potential drug than that of its prerearrangement

JIADIFENIN ANALOGS AND USES THEREOF

The present invention provides compounds having formula (I) and additionally provides methods for the synthesis thereof, compositions thereof, and methods for the use thereof in the treatment of neurodegenerative disorders, wherein R1-R6, m and n are as defined herein.

Total synthesis of (±)-jiadifenin, a non-peptidyl neurotrophic modulator

We report the first total synthesis of jiadifenin (1), the establishment of a modality for its biological evaluation, and the discovery of apparently more potent neurotrophic activity in fully synthetic compound 17, an intermediate en route to 1. Copyright