80527-42-0

Basic information

• Product Name: N-ethyl-2,3,4,5,6-pentafluorobenzamide
• Synonyms: N-ethyl-2,3,4,5,6-pentafluorobenzamide
• CAS NO: 80527-42-0
• Molecular Weight: 239.145
• Mol File: 80527-42-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-ethyl-2,3,4,5,6-pentafluorobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-ethyl-2,3,4,5,6-pentafluorobenzamide(80527-42-0)
• EPA Substance Registry System: N-ethyl-2,3,4,5,6-pentafluorobenzamide(80527-42-0)

Safety Data

• Hazardous Substances Data: 80527-42-0(Hazardous Substances Data)

Upstream product

• 2251-50-5 pentafluorobenzoylchloride 
• 75-04-7 ethylamine 
• 5796-97-4 bis(triethylsilyl) peroxide 
• 652-31-3 2,3,4,5,6-pentafluorobenzamide 

Relevant articles and documents

Bis(trialkylsilyl) peroxides as alkylating agents in the copper-catalyzed selective mono-: N -alkylation of primary amides

The copper-catalyzed selective mono-N-alkylation of primary amides with bis(trialkylsilyl) peroxides as alkylating agents was reported. The results of a mechanistic study suggest that this reaction should proceed via a free radical process that includes the generation of alkyl radicals from bis(trialkylsilyl) peroxides.

Alkylsilyl Peroxides as Alkylating Agents in the Copper-Catalyzed Selective Mono-N-Alkylation of Primary Amides and Arylamines

The copper-catalyzed selective mono-N-alkylation of primary amides or arylamines using alkylsilyl peroxides as alkylating agents is reported. The reaction proceeds under mild reaction conditions and exhibits a broad substrate scope with respect to the alkylsilyl peroxides, as well as to the primary amides and arylamines. Mechanistic studies suggest that the present reaction should proceed through a free-radical process that includes alkyl radicals generated from the alkylsilyl peroxides.