805326-33-4Relevant academic research and scientific papers
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation
Carraro, Fabio,Naldini, Antonella,Pucci, Annalisa,Locatelli, Giada A.,Maga, Giovanni,Schenone, Silvia,Bruno, Olga,Ranise, Angelo,Bondavalli, Francesco,Brullo, Chiara,Fossa, Paola,Menozzi, Giulia,Mosti, Luisa,Modugno, Michele,Tintori, Cristina,Manetti, Fabrizio,Botta, Maurizio
, p. 1549 - 1561 (2007/10/03)
We report here the synthesis of new pyrazolo[3,4-d]pyrimidine derivatives along with their biological properties as inhibitors of isolated Src and cell line proliferation (A431 and 8701-BC cells). Such compounds block the growth of cancer cells by interfe
4-SUBSTITUTED DERIVATIVES OF PYRAZOLO[3,4-d]PYRIMIDINE AND PYRROLO[2,3-d]PYRIMIDINE AND USES THEREOF
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Page 11, (2008/06/13)
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine are described. Compounds are active as antitumoural agents.
