80535-01-9

Upstream product

• 80535-32-6 chloromethyl-2 dimethyl-1,2 phenyl-4 piperidine 
• 5292-53-5 diethyl benzalmalonate 
• 80534-82-3 diethyl malonyl-1 methyl-3 phenyl-1 butene-3 
• 80535-12-2 5-Methyl-3-phenyl-hex-5-enoic acid methylamide 
• 80544-68-9 N-methyl methyl-5 phenyl-3 hexene-5 yl amine 
• 80534-91-4 N-methyl methyl-5 phenyl-3 hexene-5 yl amine 
• 100-52-7 benzaldehyde 
• 80534-87-8 methyl-5 phenyl-3 hexene-5 oate d'ethyle 

Relevant academic research and scientific papers

SYNTHESE RADICALAIRE D'ANALGESIQUES POTENTIELS: ARYL-4 PIPERIDINES SUBSTITUEES EN 2 ET BENZOMORPHANES

The synthesis of a series of 3-aryl 5-hexenyl amines and the cyclisations of the corresponding N-chloroamines are described.When the ring closure results from the amino radical addition to the ethylenic double bond, 2-chloromethyl 4-phenyl piperidines are obtained.These compounds lead by intramolecular Friedel-Crafts reaction to varied substituted 6,7-benzomorphanes.When the phenyl ring is substituted with a methoxyl group, the cyclisation proceeds via homolytic aromatic substitution and 4-allyl tetrahydroquinolines are formed.