80585-49-5Relevant academic research and scientific papers
OLIGODEOXYRIBONUCLEOTIDE SYNTHESIS BY USE OF S,S-DIPHENYL DEOXYRIBONUCLEOSIDE 3'-PHOSPHORODITHIOATES AND BIFUNCTIONAL CONDENSING REAGENTS IN THE PHOSPHOTRIESTER APPROACH
Sekine, Mitsuo,Matsuzaki, Jun-Ichi,Hata, Tsujiaki
, p. 5279 - 5288 (2007/10/02)
Four kinds of arenedisulphonyl chlorides as condensing reagents for oligodeoxyribonucleotide synthesis have been synthesised and their condensing abilities were examined in the synthesis of thymidylyl(3'-5')thymidine.Among them, mesitylenedisulphonyl chlo
Cyclic Orthoester Functions as New Protecting Groups in Nucleosides
Sekine, Mitsuo,Hata, Tsujiaki
, p. 2044 - 2049 (2007/10/02)
Four kinds of cyclic orthoester functions have been studied as protecting groups of hydroxyl groups in nucleosides.Among them, the 1,3-benzodithiol-2-yl (BDT) group was found to have several promising properties.This group can be easily introduced into nu
PHOSPHOTRIESTER APPROACH TO OLIGOTHYMIDYLATE SYNTHESIS UTILIZING A SIMPLE THYMIDINE UNIT AND A NEW TYPE OF CONDENSING AGENT
Sekine, Mitsuo,Matsuzaki, Jun-ichi,Hata, Tsujiaki
, p. 3209 - 3212 (2007/10/02)
DMTrTp(SPh)2 was proposed as a simplest "nucleotide unit" for the synthesis of olygothymidylates.One phenylthio group was removed selectively and rapidly from dithiol-esters by 1M pyridinium hypophosphonate.Two kinds of arenedisulfonyl chlorides were newl
