80595-16-0

Upstream product

• 25779-13-9 (S)-1-phenyl-1,2-ethanediol 
• 76-83-5 trityl chloride 
• 17199-29-0 (S)-Mandelic acid 

Downstream Products

• 80595-19-3 C₅₈H₅₄O₅ 
• 685836-12-8 (1S)-1-phenyl-1-O-(Z-prop-1'-en-1'-yl)-1,2-ethanediol 
• 95237-09-5 (1S)-1-O-allyl-1-phenyl-1,2-ethanediol 
• 685836-04-8 (1S,3'R,4'S)-2-O-methanesulfonyl-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-1,2-ethanediol 
• 685835-98-7 (1S)-1-phenyl-1-O-(Z-prop-1'-en-1'-yl)-2-O-(2,4,6-triisopropyl-benzenefulfonyl)-1,2-ethanediol 
• 685836-06-0 (1S,3'R,4'S)-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-2-O-(2,4,6-triisopropylbenzenesulfonyl)-1,2-ethanediol 
• 685836-05-9 (1S,3'S,4'R)-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-2-O-(2,4,6-triisopropylbenzenesulfonyl)-1,2-ethanediol 
• 80595-12-6 (S,S)-(+)-5,13-diphenyl-19-methoxy-3,6,9,12,15-pentaoxa-21-azabicyclo<15.3.1>heneicosa-1(21),17,19-triene-2,16-dione 
• 80595-14-8 (R,S)-2,10-diphenyl-3,6,9-trioxaundecane-1,11-diol 
• 80656-09-3 (R,R)-(-)-2,10-diphenyl-3,6,9-trioxaundecane-1,11-diol 
• 80656-05-9 (S,S)-(+)-9,17-diphenyl-1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione 
• 80656-06-0 (S,S)-(+)-5,13-diphenyl-3,6,9,12,15,20-hexaoxabicyclo<15.2.1>eicosa-17,19-diene-2,6-dione 
• 344344-54-3 (R,S)-5,13-diphenyl-3,6,9,12,15-pentaoxa-21-azabicyclo<15.3.1>heneicosa-1(21),17,19-triene-2,16-dione 
• 80656-07-1 (S,S)-(+)-5,13-diphenyl-3,6,9,12,15-pentaoxa-21-azabicyclo<15.3.1>heneicosa-1(21),17,19-triene-2,16-dione 

Relevant academic research and scientific papers

Synthesis, biological, and chiroptical activity of 3-phenyl-clavams

The [2+2]cycloaddition of chlorosulfonyl isocyanate to simple vinyl ethers derived from the 2-O-sulfonylated (R) and (S) 1-phenyl-1,2-ethanediol leads to 4-alkoxy-azetidin-2-ones with a moderate stereoselectivity. The cycloaddition to analogous (Z)-propenyl ethers proceeds stereospecifically with the retention of the olefin configuration. The intramolecular alkylation of β-lactam nitrogen atom furnished all possible stereoisomers of 3-phenyl- and 6-methyl-3-phenyl-clavams. The biological and chiroptical activity of synthesized clavams was investigated. The (3R,5R)-diastereomer 30 showed higher inhibition of bacterial enzymes than other related compounds.

Preparation of Chiral Diphenyl-Substituted Polyether-Diester Compounds

A new series of chiral polyether-diester ligands has been prepared by reacting racemic and chiral diphenyl-substituted tetraethylene glycols with diglycolyl chloride (5 and 6), 2,5-furandicarbonyl chloride (7 and 8), 2,6-pyridinedicarbonyl chloride (9-12), and 4-methoxy-2,6-pyridinedicarbonyl chloride (13).The chiral diphenyl-substituted tetraethylene glycols were prepared from the dl-, (S)-, and (R)-mandelic acids.