95237-09-5

Basic information

• Product Name: (1S)-1-O-allyl-1-phenyl-1,2-ethanediol
• CAS NO: 95237-09-5
• Molecular Weight: 178.231
• Mol File: 95237-09-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S)-1-O-allyl-1-phenyl-1,2-ethanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-1-O-allyl-1-phenyl-1,2-ethanediol(95237-09-5)
• EPA Substance Registry System: (1S)-1-O-allyl-1-phenyl-1,2-ethanediol(95237-09-5)

Safety Data

• Hazardous Substances Data: 95237-09-5(Hazardous Substances Data)

Upstream product

• 80595-16-0 (1S)-1-phenyl-2-O-triphenylmethyl-1,2-ethanediol 
• 25779-13-9 (S)-1-phenyl-1,2-ethanediol 
• 685836-11-7 (1S)-1-O-allyl-1-phenyl-2-O-triphenylmethyl-1,2-ethanediol 

Downstream Products

• 685836-12-8 (1S)-1-phenyl-1-O-(Z-prop-1'-en-1'-yl)-1,2-ethanediol 
• 685836-05-9 (1S,3'S,4'R)-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-2-O-(2,4,6-triisopropylbenzenesulfonyl)-1,2-ethanediol 
• 685836-06-0 (1S,3'R,4'S)-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-2-O-(2,4,6-triisopropylbenzenesulfonyl)-1,2-ethanediol 
• 685835-98-7 (1S)-1-phenyl-1-O-(Z-prop-1'-en-1'-yl)-2-O-(2,4,6-triisopropyl-benzenefulfonyl)-1,2-ethanediol 
• 685836-04-8 (1S,3'R,4'S)-2-O-methanesulfonyl-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-1,2-ethanediol 
• 685836-03-7 (1S,3'S,4'R)-2-O-methanesulfonyl-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-1,2-ethanediol 
• 685835-95-4 (1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol 

Relevant articles and documents

Synthesis, biological, and chiroptical activity of 3-phenyl-clavams

The [2+2]cycloaddition of chlorosulfonyl isocyanate to simple vinyl ethers derived from the 2-O-sulfonylated (R) and (S) 1-phenyl-1,2-ethanediol leads to 4-alkoxy-azetidin-2-ones with a moderate stereoselectivity. The cycloaddition to analogous (Z)-propenyl ethers proceeds stereospecifically with the retention of the olefin configuration. The intramolecular alkylation of β-lactam nitrogen atom furnished all possible stereoisomers of 3-phenyl- and 6-methyl-3-phenyl-clavams. The biological and chiroptical activity of synthesized clavams was investigated. The (3R,5R)-diastereomer 30 showed higher inhibition of bacterial enzymes than other related compounds.