80609-90-1Relevant academic research and scientific papers
Titania-supported iridium subnanoclusters as an efficient heterogeneous catalyst for direct synthesis of quinolines from nitroarenes and aliphatic alcohols
He, Lin,Wang, Jian-Qiang,Gong, Ya,Liu, Yong-Mei,Cao, Yong,He, He-Yong,Fan, Kang-Nian
, p. 10216 - 10220 (2011)
A versatile heterogeneous catalyst consisting of sub-nanosized iridium clusters deposited on titania (Ir/TiO2-NCs) promotes the direct tandem synthesis of quinoline derivatives from readily available nitroarenes and aliphatic alcohols under mild and additive-free conditions (see scheme). The process tolerates the presence of various reactive functional groups and is highly selective.
Ruthenium-catalyzed formal alkyl group transfer: Synthesis of quinolines from nitroarenes and alkylammonium halides
Cho, Chan Sik,Lee, Na Young,Kim, Tae-Jeong,Shim, Sang Chul
, p. 423 - 429 (2007/10/03)
Nitroarenes are reductively cyclized with an array of tetraalkylammonium halides and trialkylammonium chlorides in the presence of a catalytic amount of a ruthenium catalyst along with tin(II) chloride dihydrate at 180° to afford the corresponding quinolines in moderate to good yields. The addition of tin(lI) chloride dihydrate is necessary for the effective formation of quinolines and toluene is the solvent of choice. A reaction pathway involving initial reduction of nitroarenes to anilines and conversion of alkylammonium halides to alkylamines, alkyl group transfer from alkylamines to anilines to form an imine, dimerization of imine, and heteroannulation is proposed for this catalytic process.
