80680-06-4

Basic information

• Product Name: Tefludazine
• Synonyms: Tefludazine
• CAS NO: 80680-06-4
• Molecular Formula: C22H24F4N2O
• Molecular Weight: 408.437
• Mol File: 80680-06-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 476.4°C at 760 mmHg
• Flash Point: 241.9°C
• Appearance: /
• Density: 1.285g/cm³
• Vapor Pressure: 6.94E-10mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: Tefludazine(CAS DataBase Reference)
• NIST Chemistry Reference: Tefludazine(80680-06-4)
• EPA Substance Registry System: Tefludazine(80680-06-4)

Safety Data

• Hazardous Substances Data: 80680-06-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2/t19-,21+/m0/s1

Upstream product

• 85663-11-2 ethyl 3-<2-bromo-4-(trifluoromethyl)phenyl>-2-cyano-3-(4-fluorophenyl)propanoate 
• 80272-16-8 3-<2-bromo-4-(trifluoromethyl)phenyl>-3-(4-fluorophenyl)propanoic acid 
• 85118-34-9 ethyl 3-<2-bromo-4-(trifluoromethyl)phenyl>-2-cyano-2-propenoate 
• 80272-85-1 3-(4-fluorophenyl)-6-(trifluoromethyl)indan-1-ol 
• 85118-24-7 2-bromo-4-(trifluoromethyl)benzaldehyde 
• 80272-38-4 3-(4-fluorophenyl)-6-(trifluoromethyl)indan-1-one 
• 103-76-4 1-(2-hydroxyethyl)piperazine 
• 85118-26-9 1-chloro-3-(4-fluorophenyl)-6-(trifluoromethyl)indan 

Relevant articles and documents

Indane derivatives, pharmaceutical compositions thereof and method of preparation

The present invention relates to novel 1-piperazino-3-phenyl-indane derivatives which have pronounced psychopharmacological activity such as neuroleptic activity, analgesic activity, antidepressant activity and, at the same time, a low degree of undesired side-effects, methods for the preparation of said indane derivatives, pharmaceutical compositions containing same, and methods for the treatment of psychic disorders, such as psychoses and depressions and pain, by administering a therapeutically active amount of one of said derivatives to a living animal body, including human beings.