80685-00-3

Upstream product

• 74-85-1 ethene 
• 31350-99-9 1-[(1-bromoethyl)sulfonyl]-4-methylbenzene 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 14195-15-4 α-(p-methylbenzenesulfonyl)propiophenone 
• 1517-82-4 (-)-menthyl p-toluenesulfinate 
• 80684-96-4 (2R)-2-[(R)-p-tolylsulfinyl]butane 

Relevant academic research and scientific papers

Nickel-Catalyzed Enantioconvergent Reductive Hydroalkylation of Olefins with α-Heteroatom Phosphorus or Sulfur Alkyl Electrophiles

Substantial advances in enantioconvergent C(sp3)-C(sp3) bond formation reactions have been made in recent years through the use of transition-metal-catalyzed cross-coupling reactions of racemic secondary alkyl electrophiles with organometallic reagents. Herein, we report a general process for the asymmetric construction of alkyl-alkyl bonds adjacent to heteroatoms, namely, a nickel-catalyzed enantioconvergent reductive hydroalkylation of olefins with α-heteroatom phosphorus or sulfur alkyl electrophiles. Including the use of readily available olefins, this reaction has considerable advantages, such as mild reaction conditions, a broad substrate scope, and good functional group compatibility, making it a desirable alternative to traditional electrophile-nucleophile cross-coupling reactions.

Optical Stability of Carbanions Derived from Sulphoximides and Sulphilimines

Pairs of diastereomeric sulphoximides and sulphilimines of known absolute configuration have been converted into the corresponding carbanions, which have a definite optical stability.