80707-93-3

Usage

Classification

Synthetic compound
Belongs to the class of glycerol derivatives

Function

Surfactant and emulsifying agent

Applications

Personal care and cosmetic products
Pharmaceutical formulations

Properties

Stabilizes and emulsifies oil-in-water systems
Solubilizes poorly soluble drugs
Disperses pigments and fillers in cosmetic formulations

Safety

Deemed safe for use in cosmetics and personal care products
Approved by the Cosmetic Ingredient Review Expert Panel

Common products containing OBG

Shampoos
Skin creams
Bath products
Lotions, creams, and ointments

Upstream product

• 112-92-5 1-octadecanol 
• 84379-56-6 1-O-octadecyl-2-O-benzyl-3,4-O-isopropylidene-D-threitol 
• 100-52-7 benzaldehyde 
• 91326-83-9 (4S,5S)-dimethyl 2-phenyl-1,3-dioxolane-4,5-dicarboxylate 
• 84379-52-2 (2R,3R)-3-(benzyloxy)butane-1,2,4-triol 
• 84379-54-4 (R)-2-(benzyloxy)-2-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanol 
• 31081-59-1 1-octadecyl methanesulfonate 
• 10585-86-1 1,2-Di-O-isopropyliden-3-O-octadecyl-sn-glycerin 
• 83526-60-7 2-O-Acetyl-1-O-benzyl-3-O-octadecyl-sn-glycerin 
• 83526-52-7 3-O-Octadecyl-2-O-p-toluolsulfonyl-sn-glycerin 
• 83526-54-9 3-O-Octadecyl-1-O-p-toluolsulfonyl-sn-glycerin 
• 83537-01-3 (-)-1-O-octadecyl-2-O-acetyl-sn-glycerol 
• 83526-56-1 (S)-1,2-Epoxy-3-(octadecyloxy)propan 
• 83526-51-6 3-O-Octadecyl-2-O-p-toluolsulfonyl-3-O-trityl-sn-glycerin 

Downstream Products

• 80459-32-1 (2R)-2-Benzyloxy-3-octadecyloxypropyl 2-bromoethyl phosphate 
• 99804-87-2 (R)-2-O-benzyl-1-[(2-bromoethoxy)carbonyl]-3-O-octadecylglycerine 
• 83167-59-3 1-O-octadecyl-2-O-methyl-sn-glycerol 
• 99804-98-5 (R)-2-O-benzyl-1-O-[(2-chloroethyl)carbamoyl]-3-O-octadecylglycerine 
• 99804-86-1 (R)-2-O-benzyl-1-O-(4-chlorobutyryl)-3-O-octadecylglycerine 
• 80483-86-9 2-O-Benzyl-1-O-octadecyl-sn-glycero-3-phosphorylcholin 
• 74389-69-8 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 
• 74430-89-0 Lyso-platelet-activating factor (C₁₈) 
• 918946-93-7 Phosphoric acid (R)-2-benzyloxy-3-octadecyloxy-propyl ester (S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester 
• 1026554-06-2 Phosphoric acid (R)-2-benzyloxy-3-octadecyloxy-propyl ester (S)-2,3-dihydroxy-propyl ester 
• 105415-93-8 (R)-2-benzyloxy-3-octadecyloxypropyl 2-(N-methylpyrrolidinio)ethyl phosphate 
• 105435-57-2 (R)-2-benzyloxy-3-octadecyloxypropyl 2-(diethylmethylammonio)ethyl phosphate 

Relevant academic research and scientific papers

Synthesis and biological activity of anticancer ether lipids that are specifically released by phospholipase A2 in tumor tissue

The clinical use of anticancer lipids is severely limited by their ability to cause lysis of red blood cells prohibiting intravenous injection. Novel delivery systems are therefore required in order to develop anticancer ether lipids (AELs) into clinicall

Chiral PAF agonists: Synthesis, theoretical analysis of their stereoelectronic properties and structure activity relationships

A series of chiral PAF agonists were synthesized. Modifications at the PAF structure were undertaken as far as the C2 substituents and the onium head groups are concerned. In parallel, molecular modelling studies including a MOPAC geometry optimization and the analysis of the electrostatic potential were performed on the newly synthesized and on already known PAF agonists, in order to gain a better insight into the stereoelectronic features required for interaction with the PAF receptor.

Method of use of 1-(alkyl for alkylcarbanoyl)-2-carbamoylglycerol derivatives

Glycerol derivatives, inclusive of salts thereof, of the formula STR1 wherein R1 is alkyl or alkylcarbamoyl containing 10 to 30 carbon atoms, R2 and R3 are independently hydrogen, C1-6 alkyl or, taken together w

Stereoselective Synthesis of Long-chain 1-O-(β-D-Maltosyl)-3-O-alkyl-sn-glycerols (Alkyl Glyceryl Ether Lysoglycolipids)

The synthesis of long-chain 2-O-benzyl-3-O-alkyl-sn-glycerols 5 was improved, making these compounds easily accessible for glycosylation experiments.Glycosylation with α-acetobromomaltose following a modified Koenings-Knorr procedure after removal of the protective groups yielded the title compound 9 in good yields.These compounds represent examples of alkyl glyceryl ether lysoglycolipids.Some properties of these amphiphilic compounds with a nonionic carbohydrate head-group differ not much (critical micell concentration, hemolytic activity), other properties differ very much (antitumor efficiency) from the properties of the analogous compounds with a zwitterionic phosphorylcholine head-group.