38169-74-3Relevant academic research and scientific papers
Synthesis of glyceryl ethers in high optical purity via ruthenium catalyzed asymmetric hydrogenation
Cesarotti, Edoardo,Mauri, Angela,Pallavicini, Marco,Villa, Luigi
, p. 4381 - 4384 (2007/10/02)
1-O-octadecyl-3-O-trityl-glycerol and 1-O-benzyl-3-O-trityl-glycerol can be prepared by asymmetric catalytic hydrogenation in O.P.> 96% and 87-88% respectively.
An efficient synthesis of Platelet-Activating Factor (PAF) via 1-o-alkyl-2-o-(3-isoxazolyl)-SN-glycero-3-phosphocholine, a new PAF agonist utilization of the 3-isoxazolyloxy group as a protected hydroxyl
Nakamura, Norio,Miyazaki, Hideki,Ohkawa, Nobuyuki,Oshima, Takeshi,Koike, Hiroyuki
, p. 699 - 702 (2007/10/02)
Potent PAF agonists (R)-3a,b were synthesized and converted into PAF. Key steps include Mitsunobu reaction of a chiral secondary alcohol with 3-hydroxyisoxazole as the acidic component, and hydrogenolytic ring cleavage of the resulting 3-isoxazolyloxy gro
