80744-01-0

Usage

Uses

Used in Pharmaceutical Industry:
1H-Indole-2-carboxaldehyde, 4,5,6,7-tetrahydro(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals. Its chemical structure allows it to be a building block for the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 1H-Indole-2-carboxaldehyde, 4,5,6,7-tetrahydro- (9CI) serves as an intermediate for the production of agrochemicals. Its involvement in this industry is crucial for the development of pesticides and other agricultural products that are essential for crop protection and yield enhancement.
Used in Dye Production:
1H-Indole-2-carboxaldehyde, 4,5,6,7-tetrahydro(9CI) is utilized in the creation of dyes, where its chemical properties enable the production of a range of colorants used in various applications, including textiles, plastics, and printing inks.
Used in Perfumery:
1H-Indole-2-carboxaldehyde, 4,5,6,7-tetrahydro(9CI) is also employed in the perfume industry, where it contributes to the development of unique fragrances. Its chemical composition allows it to be a component in complex scent profiles, adding depth and character to perfumes.
Used in Flavoring Agents:
Lastly, 1H-Indole-2-carboxaldehyde, 4,5,6,7-tetrahydro(9CI) is used in the flavor and fragrance industry to create flavoring agents. Its ability to impart specific tastes and smells makes it a valuable ingredient in the formulation of food and beverage products, as well as in the creation of scented products such as candles and air fresheners.

Upstream product

• 82826-29-7 2-(2-Hydroxy-ethylamino)-cyclohex-1-enecarboxylic acid methyl ester 
• 13618-91-2 4,5,6,7-tetrahydroindole 
• 68-12-2 N,N-dimethyl-formamide 
• 51050-85-2 1-vinyl-4,5,6,7-tetrahydroindole 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 41302-34-5 2-(methoxycarbonyl)cyclohexanone 
• 100-64-1 cyclohexanone-oxime 
• 108-94-1 cyclohexanone 
• 13754-86-4 1,5,6,7-tetrahydro-indol-4-one 
• 127441-69-4 β-hydroxyethylamino-2 cyclohexene-1 carboxylate d'ethyle 

Downstream Products

• 288144-20-7 VEGFR receptor tyrosine kinase inhibitor II 
• 1204655-07-1 N-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)benzene-1,2-diamine 

Relevant academic research and scientific papers

Synthesis and Photochemical Properties of 2,3;5,6-bis(cyclohexano)-BODIPY

The boron-dipyrromethene (BODIPY) dye containing an annelated cyclohexyl rings at the 2,3 and 5,6-positions of pyrroles has been synthesized and characterized. Photochemical properties of the obtained compound have been investigated in different individua

Isothiourea-catalysed enantioselective pyrrolizine synthesis: Synthetic and computational studies

The catalytic enantioselective synthesis of a range of cis-pyrrolizine carboxylate derivatives with outstanding stereocontrol (14 examples, >95:5 dr, >98:2 er) through an isothiourea-catalyzed intramolecular Michael addition-lactonisation and ring-opening

COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASE

Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.

A new synthesis of symmetric boraindacene (BODIPY) dyes

BODIPY dyes were synthesized from pyrrole-2-carbaldehyde derivatives in high yields; this constitutes a new approach to this dye framework. The Royal Society of Chemistry.

Expedient synthesis of 1-vinylpyrrole-2-carbaldehydes

1-Vinylpyrrole-2-carbaldehydes and 1-vinyl-4,5-dihydrobenzo[g]indole-2-carbaldehyde were synthesized in 56-91% yields from their 1-vinyl derivatives by a modified Vilsmeier-Haack reaction. A low temperature (-78 °C) is required to avoid removal of the N-v

Identification of substituted 3-[(4,5,6,7-tetrahydro-1H- indol-2-yl)methylene]-1,3-dihydroindol-2-ones as growth factor receptor inhibitors for VEGF-R2 (Flk-1/KDR), FGF-R1, and PDGF-Rβ tyrosine kinases

A series of new 3-substituted indolin-2-ones containing a tetrahydroindole moiety was developed as specific inhibitors of receptor tyrosine kinases associated with VEGF-R, FGF-R, and PDGF-R growth factor receptors. These compounds were evaluated for their

Synthese de derives indoliques, d'oxazoles et de quinolones par thermolyse d'enaminoesters cycliques a cinq et six chainons

Flow pyrolysis of cyclic enaminoesters 1-9 provides various heterocyclic compounds resulting from intramolecular thermal rearrangement of intermediate iminoketenes generated in the first reaction step.The thermal behaviour of these cyclic enaminoesters is

THERMOLYSE COMPAREE D'ENAMINOESTERS CYCLIQUES A CINQ ET SIX CHAINONS : SYNTHESE DE TETRAHYDROINDOLES ET D'OXAZOLES

The thermal behaviour of cyclic enaminoesters 1a-d shows a divergence of chemioselectivity as a function of ring size : six and five ring derivatives lead respectively to tetrahydroindoles (3a,b and 4a,b) and oxazole (5c,d).These results may be rationalized by geometrical constraints during the electrocyclisation of intermediate azomethine ylides 5.