80795-54-6

Upstream product

• 16054-77-6 (3R,4S,5R)-4-(benzyloxy)-5-(benzyloxymethyl)tetrahydrofuran-2,3-diol 
• 100-39-0 benzyl bromide 
• 561055-45-6 (3R,4S,5R)-4-(benzyloxy)-5-(benzyloxymethyl)tetrahydrofuran-2,3-diol 
• 55735-86-9 3,5-O-dibenzyloxy-1,2-O-isorpopylidene-α-D-ribofuranose 

Downstream Products

• 80765-79-3 1,3,5-tri-O-benzyl-2-O-(trifluoromethanesulfonyl)-α-D-ribofuranose 
• 950839-32-4 1,3,5-tri-O-benzyl-2-O-acetyl-α-D-ribofuranose 
• 80765-80-6 2-fluoro-2-deoxy-1,3,5-tri-O-benzoyl-α-D-arabinofuranose 
• 80765-81-7 (2S,3S,4R,5R)-2,4-Bis-benzyloxy-5-benzyloxymethyl-3-chloro-tetrahydro-furan 
• 80765-82-8 (2S,3S,4R,5R)-2,4-Bis-benzyloxy-5-benzyloxymethyl-3-bromo-tetrahydro-furan 
• 80765-83-9 (2S,3S,4R,5R)-2,4-Bis-benzyloxy-5-benzyloxymethyl-3-iodo-tetrahydro-furan 
• 80765-84-0 (2S,3S,4S,5R)-3-Azido-2,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan 
• 1443748-53-5 1,2-di-O-acetyl-3,5-di-O-benzyl-β-D-ribofuranose 

Relevant academic research and scientific papers

O-acetyl-ADP-ribose non-hydrolyzable analogs

Compounds, compositions and methods for modulating cell death in target cells, particularly cancer cells are provided. The compounds are analogs of O-acetyl-ADP-ribose (OAADPr).

Synthesis and biochemical evaluation of O-acetyl-ADP-ribose and N-acetyl analogs

Synthetic routes for the preparation of O-acetyl-ADP-ribose and two novel non-hydrolyzable analogs containing an N-acetyl are described and shown to interact with the macro domain of histone protein H2A1.1. The Royal Society of Chemistry.