808134-47-6Relevant academic research and scientific papers
Discovery of N1-(6-Chloroimidazo[2,1-b][1,3]-thiazole-5- sulfonyl)tryptamine as a potent, selective, and orally active 5-HT6 receptor agonist
Cole, Derek C.,Stock, Joseph R.,Lennox, William J.,Bernotas, Ronald C.,Ellingboe, John W.,Boikess, Steve,Coupet, Joseph,Smith, Deborah L.,Leung, Louis,Zhang, Guo-Ming,Feng, Xidong,Kelly, Michael F.,Galante, Rocco,Huang, Pingzhong,Dawson, Lee A.,Marquis, Karen,Rosenzweig-Lipson, Sharon,Beyer, Chad E.,Schechter, Lee E.
, p. 5535 - 5538 (2007)
N1-Arylsulfonyltryptamines have been identified as 5-HT 6 receptor ligands. In particular, N1(6-chloroimidazo[2,1- b][1,3]thiazole-5-sulfonyl)tryptamine (11q) is a high affinity, potent full agonist (5-HT6 Ksub
A Facile Synthesis of 3-Substituted Indoles
Nagarathnam, Dhanapalan
, p. 953 - 958 (2007/10/02)
1-Benzoyl-3-bromomethylindole (2a) or 1-benzenesulfonyl-3-bromomethylindole (2b) reacts with C, N, O, and P-containing nucleophiles to give potential intermediates for the synthesis of a wide range of indole alkaloids and pharmacologically important substances, in good to excellent yields.
