80823-69-4Relevant academic research and scientific papers
Aldol additions of pinacolone lithium enolate with ketones: Reactivities governed predominantly by field effects
Das, Goutam,Thornton, Edward R.
, p. 1302 - 1312 (1993)
The relative reactivities of representative α- and β-heterosubstituted acyclic, cyclic (five- and six-membered), and aromatic ketones with the lithium enolate of pinacolone in diethyl ether at -78 °C were determined. The order of reactivities of monosubst
MIXED KETONE-KETONE CONDENSATIONS UNDER THE CONDITIONS OF THE GRIGNARD-COLONGE METHOD
Sosnovskikh, V. Ya.,Esafov, V. I.,Andreev, N. S.
, p. 2096 - 2100 (2007/10/02)
The mixed condensation of aliphatic and aromatic methyl ketones was realized under the conditions of the Grignard-Colonge method.By dehydration of the synthesized β-ketols the β-methyl-α,β-unsaturated ketones with a sterically hindered carbonyl group were obtained.
